Case Report: A Cluster of Three Leptospirosis Cases in a New York City Abattoir and an Unusual Complication in the Index Case

Tania Kupferman Division of Infectious Diseases and Immunology, NYU School of Medicine, New York, New York;

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Megan P. Coffee Division of Infectious Diseases and Immunology, NYU School of Medicine, New York, New York;
International Rescue Committee, New York, New York

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Benjamin J. Eckhardt Division of Infectious Diseases and Immunology, NYU School of Medicine, New York, New York;

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We report the case of a 46-year-old male abattoir worker who developed myalgias, shortness of breath, and irritability 2 weeks after sustaining a laceration to the hand with a knife at work. During his hospital evaluation for septic shock he was noted to be febrile, hypotensive, profoundly jaundiced with aseptic meningitis, and renal failure, and was diagnosed with Leptospirosis interrogans infection confirmed by serum and urine polymerase chain reaction. After standard antibiotic therapy and recovery from severe clinical illness, he developed unilateral orchitis with pyuria secondary to leptospirosis, a well-established complication in the veterinary literature, but of which we offer the first report in humans in the English literature. The case presented was also the index case that uncovered a cluster outbreak of leptospirosis in New York City during the winter of 2016–2017, involving a total of three patients who lived or worked within a block of the abattoir. Two patients survived whereas the third died of pulmonary hemorrhage shortly after seeking medical care.

Author Notes

Address correspondence to Tania Kupferman, Bellevue Hospital Center, NYU School of Medicine, 550 First Ave 16S 5-13, New York, NY 10016. E-mail: tania.kupferman@nyumc.org

Authors’ addresses: Tania Kupferman, NYU School of Medicine, Bellevue Hospital Center, Infectious Diseases, New York, NY, E-mail: tania.kupferman@nyumc.org. Megan P. Coffee, Bellevue Hospital Center, Infectious Diseases, New York, NY and International Rescue Committee, New York, NY, E-mail: megan.coffee@nyumc.org. Benjamin J. Eckhardt, Bellevue Hospital Center, Infectious Diseases, New York, NY, E-mail: benjamin.eckhardt@nyumc.org.

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