1.Carbon tetrachlorid in diminished doses, when used in the treatment of hookworm disease, has a selective action upon female hookworms and does not remove ascarides.
2.Ascaridol, the active principle of chenopodium, in diminished doses has a selective action upon male hookworms and is remarkably efficient in removing ascarides.
3.A mixture of the two drugs does not increase their toxicity toward the host, since carbon tetrachlorid has a specific action upon the liver, whereas ascaridol affects chiefly the central nervous system.
4.An anthelmintic approaching the ideal for field treatment of hookworm disease is obtained by administering 2 cc. of a mixture containing 4 parts carbon tetrachlorid and 1 part ascaridol. The mixture is highly efficient, comparatively non-toxic, easy to administer, and inexpensive.