The Active Form of Tryparsamide, TPB, in the Treatment of Human Trypanosomiasis

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Summary

TPB represents the “active form”, i.e. the arsenoxide of tryparsamide in a stabilized and detoxified form, combining high trypanocidal activity towards the trypanosomes in blood and lymph and CSF, with the propensity to clear up readily the trypanosome meningo-encephalitis.

TPB is without effect on tryparsamide resistant trypanosomes.

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