Malaria Prophylaxis with Chinoplasmin

A Field Experiment

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  • 1 Rockefeller Foundation, Manilla, Philippine Islands
  • 2 United States Army Medical Department Research Board, Manilla, Philippine Islands


Daily doses of 0.01 gram of plasmochin and 0.3 gram of quinine sulphate in the form of tablets of chinoplasmin are not always sufficient to prevent the appearance of malaria parasites in the blood, although they occasionally do so and will usually forestall clinical symptoms. Such doses are well tolerated for periods up to fifty-seven days.

Even doses of 0.02 gram of plasmochin and 0.6 gram of quinine sulphate permit the occasional development of malaria parasites in the blood.