Cultivation of B. Leprae with Experimental Lesions in Monkeys

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Summary

The experiments described include (1) the experimental production of granulomatous lesions suggestive of early lesions of leprosy in two species of monkeys by intradermal inoculation of human leprosy material; (2) the cultivation of acid-fast (presumably B. leprae) bacilli from human leprosy nodules on several artificial mediums in various gaseous environments; and (3) the experimental production of granulomatous lesions, suggestive of early leprosy, in two species of monkeys by the intradermal inoculation of cultures of acid-fast bacilli from human leprosy material grown on artificial mediums. We believe the experiments indicate a step forward in the fulfillment of Koch's postulates for the causative agent in the disease of leprosy.

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