Case Report: Neurobrucellosis Presenting as Malignancy

Andrea S. Salcedo Universidad Peruana de Ciencias Aplicadas, Lima, Peru;

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Xosse Carreras Universidad Peruana de Ciencias Aplicadas, Lima, Peru;

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Takaaki Kobayashi Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa;

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Jorge L. Salinas Stanford University, Stanford, California;

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Sara Muñoz Clinica Good Hope, Lima, Peru;

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Nelson Diaz Universidad Peruana Union, Lima, Peru and Clinica Good Hope, Lima, Peru;

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Jorge Alave Universidad Peruana Union, Lima, Peru

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Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.

Author Notes

Disclosure: The patient’s written consent was obtained. Local committee approval does not apply in this case.

Authors’ addresses: Andrea S. Salcedo, and Xosse Carreras, Universidad Peruana de Ciencias Aplicadas, Lima, Peru, E-mails: andreasalcedo1697@gmail.com, and xossecarreras@gmail.com. Takaaki Kobayashi, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, E-mail: takaaki-kobayashi@uiowa.edu. Jorge L. Salinas, Stanford University, Stanford, CA, E-mail: jlsalinas@stanford.edu. Sara Muñoz, Clinica Good Hope, Lima, Peru, E-mail: sevensara@hotmail.com. Nelson Diaz, Universidad Peruana Union, Lima, Peru and Clinica Good Hope, Lima, Peru, E-mail: coordinador.medicina.int@goodhope.org.pe. Jorge Alave, Universidad Peruana Union, Lima, Peru, E-mail: jorgealave@upeu.edu.pe.

Address correspondence to Jorge Alave, Universidad Peruana Union, Carretera Central Km 19.5 Naña, Chosica, Lima 15464, Peru. E-mail: jorgealave@upeu.edu.pe
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