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Case Report: Autoimmune Pulmonary Alveolar Proteinosis after COVID-19: A Report of Two Cases
Aatish Saraswat
Aatish Saraswat
Department of Pathology, Armed Forces Medical College, Pune, India;
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Indramani Pandey
Indramani Pandey
Department of Pulmonary Medicine, Critical Care and Sleep Medicine, Armed Forces Medical College, Pune, India;
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Simple Gupta
Simple Gupta
Department of Ophthalmology, Armed Forces Medical College, Pune, India
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Manish Singh
Manish Singh
Department of Pulmonary Medicine, Critical Care and Sleep Medicine, Armed Forces Medical College, Pune, India;
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Deepu Peter
Deepu Peter
Department of Pulmonary Medicine, Critical Care and Sleep Medicine, Armed Forces Medical College, Pune, India;
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Autoimmunity has been extensively established as a characteristic feature of the post-COVID-19 syndrome. There is evolving evidence of immune system dysregulation leading to the development of autoimmune phenomena in patients with COVID-19. This immune dysregulation may range from the production of autoantibodies to the new onset of rheumatic autoimmune diseases. An extensive literature search in databases from December 2019 to date revealed that no cases of autoimmune pulmonary alveolar proteinosis (PAP) were reported in post-COVID patients. In this context, we report a novel case series of two cases of new-onset autoimmune PAP in post-COVID patients, an entity that has not been described before. We recommend further studies to better understand this association between new-onset autoimmune PAP and SARS-CoV-2.
Author Notes
Authors’ addresses: Aatish Saraswat, Department of Pathology, Armed Forces Medical College, Pune, India, E-mail: aatish.afmc@gmail.com. Indramani Pandey, Manish Singh, Deepu Peter, Department of Pulmonary Medicine, Critical Care and Sleep Medicine, Armed Forces Medical College, Pune, India, E-mails: pandey4373@gmail.com, manish.6026@gmail.com, and drdeepupeter@gmail.com. Simple Gupta, Department of Ophthalmology, Armed Forces Medical College, Pune, India, E-mail: drsimplegupta7402@gmail.com.
| Past two years | Past Year | Past 30 Days | |
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| PDF Downloads | 411 | 125 | 8 |