Vaccine coverage and timeliness are critical metrics for evaluating the performance of immunization programs. Following the introduction of rotavirus vaccine in Bamako, Mali, we conducted two cluster surveys spaced approximately 1 year apart to evaluate these metrics among children 9 to 20 months of age. Using the child’s immunization card or the medical record at the center of administration, each selected child’s immunization status was determined at 9 and 12 months of age. Deviations from the WHO-recommended immunization schedule were described by the median delay and fraction of children receiving doses outside of recommended age ranges. Overall, 1,002 children were enrolled in the two surveys combined; 80.1% of children born 7 to 12 months after introduction (survey 1) received three doses of pentavalent rotavirus vaccine (ROTA3) by 9 months of age, which increased to 86.1% among children born 17 to 26 months after introduction (survey 2). Concomitantly, coverage with the third dose of diphtheria-pertussis-tetanus-containing vaccine (DPT3) by age 9 months was 86.5% (survey 1) and 88.9% (survey 2); by age 12 months, 61.3% and 72.4% of children, respectively, had received all scheduled immunizations. The median delay in ROTA3 and DPT3 administration were similar at about 3.4 weeks. Within 3 years of introduction, coverage of rotavirus vaccine among Bamako infants achieved coverage similar to DPT3 and is approaching the Global Vaccine Action Plan goal of 90% coverage by 2020. However, timeliness of coverage remains a concern.
Address correspondence to Karen Kotloff, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore Street, HSF 480, Baltimore, MD 21201. E-mail: firstname.lastname@example.org
Financial support: This work was supported by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ.
Authors’ addresses: Anna Roose, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, and currently at Indiana University School of Medicine, Indiana University, Indianapolis, IN, E-mail: email@example.com. Uma Onwuchekwa and Samba Sow, Centre for Vaccine Development, Bamako, Mali, E-mails: firstname.lastname@example.org and email@example.com. Milagritos Tapia and Karen Kotloff, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, and Department of Pediatrics and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, E-mails: firstname.lastname@example.org and email@example.com. T. Mast, Department of Pharmacoepidemiology, Merck & Co., Inc., North Wales, PA, E-mail: firstname.lastname@example.org.