Case Report: Dengue and COVID-19 Coinfection in Thailand

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  • 1 Division of Infectious Disease, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand;
  • 2 Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;
  • 3 Vibhavadi Hospital, Bangkok, Thailand

We report a 50-year-old Thai woman with recent travel to Denmark who presented with acute high-grade fever, vomiting, and myalgia for 1 day. Initial laboratory results revealed leukopenia, elevated aspartate transaminase, and elevated alanine transaminase. Chest radiograph showed no pulmonary infiltration. Reverse transcriptase–PCR (RT-PCR) of the nasopharyngeal swab detected SARS-CoV-2, and RT-PCR of the blood detected dengue virus serotype 2. COVID-19 with dengue fever co-infection was diagnosed. Her symptoms were improved with supportive treatment. Integration of clinical manifestations, history of exposure, laboratory profiles, and dynamic of disease progression assisted the physicians in precise diagnosis. Co-circulating and nonspecific presentations of dengue infection and COVID-19 challenge the healthcare system in tropical countries. To solve this threat, multi-sector strategies are required, including public health policy, development of accurate point-of-care testing, and proper prevention for both diseases.

Author Notes

Address correspondence to Danabhand Phiboonbanakit, Division of Infectious Disease, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, 315 Ratchawithi Rd., Ratchathewi, Bangkok 10400, Thailand or Vibhavadi Hospital, 51/3 Ngamwongwan Rd., Lat Yao, Chatuchak, Bangkok, 10900, Thailand. E-mail: pdanabhand@gmail.com

Authors’ addresses: Worapong Nasomsong, Division of Infectious Disease, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand, E-mail: nasomsong.w@gmail.com. Viravarn Luvira, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, E-mail: viravarn.luv@mahidol.ac.th. Danabhand Phiboonbanakit, Division of Infectious Disease, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand, and Vibhavadi Hospital, Bangkok, Thailand, E-mail: pdanabhand@gmail.com.

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