We would like to acknowledge Epidemiology and Diseases Control Division, Ministry of Health and Population for providing national malariometric data. We are thankful to Rajendra Mishra and Uttam Pyakurel, vector control officer from EDCD, for their contribution. We are grateful to Hemraj Joshi, Hari Bhatta, and Bed Ghimire, vector control officer of Kanchanpur, Kailali, and Jhapa districts, respectively, for their help during the entire study period. We are grateful to Shiva Pokharel for creating the GIS maps of endemic districts.
WHO, 2017. World Malaria Report 2017. Geneva, Switzerland: World Health Organization. Available at: http://www.who.int/malaria/publications/world-malaria-report-2017/en/. Accessed February 11, 2018.
EDCD (Epidemiology and Disease Control Division), 2013. Final Report of Microstartification of Malaria Risk in Nepal. Ministry of Health and Population, Goverenment of Nepal. Available at: http://edcd.gov.np/public/uploads/attachments/1505034628.pdf. Accessed January 10, 2018.
EDCD (Epidmiology and Diseases Control Division), 2011. Nepal Malaria Strategic Plan 2011–2016. Ministry of Health Population, Government of Nepal. Available at: http://static1.1.sqspcdn.com/static/f/471029/20810332/1351638302043/Nepal+Strategic+Plan+2011-1016.pdf?token=nWYAdQ7Y9YMVX0ydfBODxHdOxFQ%3D. Accessed January 15, 2018.
EDCD (Epidemiology and Diseases Control Division), 2007. The Internal Assessment of Malaria and Kala-Azar Control Activities 2004, 2005 and 2006. Department of Health services, Ministry of Health and Population, Government of Nepal. Available at: https://www.nepjol.info/index.php/KUMJ/article/download/3225/2799. Accessed January 25, 2018.
EDCD (Epidemiology and Diseases Control Division), 2011. Nepal Malaria Strategic Plan 2011–2016 (Revisied Version, December 2011). Department of Health Services, Ministry of Health and Population, Government of Nepal. Available at: http://static1.1.sqspcdn.com/static/f/471029/20810332/1351638302043/Nepal+Strategic+Plan+2011-1016.pdf?token=nWYAdQ7Y9YMVX0ydfBODxHdOxFQ%3D. Accessed January 15, 2018.
Howes RE, Battle KE, Mendis KN, Smith DL, Cibulskis RE, Baird JK, Hay SI, 2016. Global epidemiology of Plasmodium vivax. Am J Trop Med Hyg 95: 15–34.
Price RN, von Seidlein L, Valecha N, Nosten F, Baird JK, White NJ, 2014. Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysis. Lancet Infect Dis 14: 982–991.
Battle KE, Gething PW, Elyazar IRF, Moyes CL, Sinka ME, Howes RE, Guerra CA, Price RN, Baird JK, Hay SI, 2012. Chapter one—the global public health significance of Plasmodium vivax. Hay SI, Rick P, Baird JK, eds. Advances in Parasitology, Vol. 80. London, United Kingdom: Academic Press, 1–111.
Mishra SR, Dhimal M, Guinto RR, Adhikari B, Chu C, 2016. Threats to malaria elimination in the Himalayas. Lancet Glob Health 4: e519.
Ghimire P, Singh N, Ortega L, Rijal KR, Adhikari B, Thakur GD, Marasini B, 2017. Glucose-6-phosphate dehydrogenase deficiency in people living in malaria endemic districts of Nepal. Malar J 16: 214.
Baird JK, 2015. Point-of-care G6PD diagnostics for Plasmodium vivax malaria is a clinical and public health urgency. BMC Med 13: 296.
Thapa S, Hollander J, Linehan M, Cox-Singh J, Bista MB, Thakur GD, Davis WA, Davis TM, 2007. Comparison of artemether-lumefantrine with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in eastern Nepal. Am J Trop Med Hyg 77: 423–430.
Wijeyaratne PM, Chand PB, Valecha N, Shahi B, Adak T, Ansari MA, Jha J, Pandey S, Bannerjee S, Bista MB, 2005. Therapeutic efficacy of antimalarial drugs along the eastern Indo-Nepal border: a cross-border collaborative study. Trans R Soc Trop Med Hyg 99: 423–429.
EDCD (Epidemiology and Diseases Control Division), 2013. Nepal Malaria Report 2010–2012. Epidemiology and Diseases Control Division, Department of Health Services, Ministry of Health and Population, Government of Nepal. Available at: http://dohs.gov.np/ne/divisions/edcd/. Accessed January 15, 2018.
WHO, 2016. Malaria Terminology. Geneva, Switzerland: World Helath Organization. Available at: http://apps.who.int/iris/bitstream/handle/10665/208815/WHO_HTM_GMP_2016.6_eng.pdf. Accessed January 25, 2018.
Pant BD, 2009. Malaria Resurgence in Nepal: An Overview. Akhtar R, Dutt A, Wadhwa V, eds. Malaria in South Asia. Advances in Asian Human-Environmental Research, Vol. 1. Dordrecht, Germany: Springer, 77–86.
SEARO (South East Asia Regional Office of WHO), 2010. Nepal Malaria Program Review. World Health Organization, Regional office for South-east Asia. New Delhi, India: SEARO. Available at: apps.searo.who.int/PDS_DOCS/B4673.pdf. Accessed April 11, 2018.
Parajuli M, Shrestha S, Vaidya R, White G, 1981. Nation-wide disappearance of Anopheles minimus Theobald, 1901, previously the principal malaria vector in Nepal. Trans R Soc Trop Med Hyg 75: 603.
Anvikar AR, Shah N, Dhariwal AC, Sonal GS, Pradhan MM, Ghosh SK, Valecha N, 2016. Epidemiology of Plasmodium vivax malaria in India. Am J Trop Med Hyg 95: 108–120.
EDCD (Epidemiology and Diseases Control Division), 2010. Internal Assessment of Malaria Control and Kala-Azar Elimination Activities 2007, 2008 and 2009. Department of Health Services, Ministry of Health and Population, Government of Nepal. Available at: http://www.dohs.gov.np/wpcontent/uploads/2014/04/Internal_assessment_5.doc. Accessed January 15, 2018.
WHO, 1979. Seventeenth Report of the WHO Expert Committee on Malaria, Technical Report Series No. 640. Geneva, Switzerland: World Health Organization.
Najera JA, Gonzalez-Silva M, Alonso PL, 2011. Some lessons for the future from the global malaria eradication programme (1955–1969). PLoS Med 8: e1000412.
Shrestha SL, Parajuli MB, 1980. Reappearance of malaria in Terai area of Nepal and incrimination of A. annularis Vander Wulp. J Nepal Med Assoc 18: 11–18.
DoHS (Department of Health Services), 2014. Annual Report 2069/2070(2012/2013). Ministry of Health and Population, Government of Nepal. Available at: http://dohs.gov.np/wp-content/uploads/2014/04/Annual_Report_2069_70.pdf. Accessed January 25, 2018.
EDCD (Epidemiology and Diseases Control Division), 2009. National Malaria Treatment Protocol. Department of Health Services, Ministry of Health and Population, Government of Nepal. Available at: http://www.worldcat.org/title/national-malaria-treatment-protocol/oclc/767875173&referer=brief_results. Accessed January 25, 2018.
EDCD (Epidemiology and Diseases Control Division), 2015. National Malaria Treatment Protocol-2015. Department of Health Services Ministry of Health and Population, Government of Nepal. Available at: http://www.searo.who.int/nepal/documents/communicable_diseases/national_malaria_treatment_protocol_2015_(revised-final).pdf. Accessed January 30, 2018.
Banjara MR, Sirawaraporn W, Petmitr S, Imwong M, Joshi AB, Chavalitshewinkoon-Petmitr P, 2009. Characteristics and risk factors of Plasmodium falciparum malaria in eastern and central Nepal. Kathmandu Univ Med J 7: 378–382.
Peto TJ 2016. History of malaria treatment as a predictor of subsequent subclinical parasitaemia: a cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia. Malar J 15: 240.
Tripura R 2016. Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies. Malar J 15: 181.
EDCD (Epidemiology and Diseases Control Division), 2013. Nepal Malaria Report 2010–2012. Kathmandu, Nepal: Department of Health Services, Ministry of Health and Population, Government of Nepal.
Dhimal M, Ahrens B, Kuch U, 2014. Malaria control in Nepal 1963–2012: challenges on the path towards elimination. Malar J 13: 241.
Vaidya NK, Wu J, 2011. HIV epidemic in far-western Nepal: effect of seasonal labor migration to India. BMC Public Health 11: 310.
Krishna CP, Masamine J, Junko O, Mahesh S, Kalpana Poudel T, Susumu W, 2004. Migration in far western Nepal: a time bomb for a future HIV/AIDS epidemic? Trop Doct 34: 30–31.
Yangzom T, Gueye CS, Namgay R, Galappaththy GN, Thimasarn K, Gosling R, Murugasampillay S, Dev V, 2012. Malaria control in Bhutan: case study of a country embarking on elimination. Malar J 11: 9.
Wickramage K, Galappaththy GN, 2013. Malaria burden in irregular migrants returning to Sri Lanka from human smuggling operations in west Africa and implications for a country reaching malaria elimination. Trans R Soc Trop Med Hyg 107: 337–340.
Abeyasinghe RR, Galappaththy GN, Smith Gueye C, Kahn JG, Feachem RG, 2012. Malaria control and elimination in Sri Lanka: documenting progress and success factors in a conflict setting. PLoS One 7: e43162.
Wang X 2016. Effects of a malaria elimination program: a retrospective study of 623 cases from 2008 to 2013 in a Chinese county hospital near the China–Myanmar border. Emerg Microbes Infect 5: e6.
Parizo J, Sturrock HJ, Dhiman RC, Greenhouse B, 2016. Spatiotemporal analysis of malaria in Urban Ahmedabad (Gujarat), India: identification of hot spots and risk factors for targeted intervention. Am J Trop Med Hyg 95: 595–603.
Sturrock HJ, Roberts KW, Wegbreit J, Ohrt C, Gosling RD, 2015. Tackling imported malaria: an elimination endgame. Am J Trop Med Hyg 93: 139–144.
Adhikari B, James N, Newby G, von Seidlein L, White NJ, Day NP, Dondorp AM, Pell C, Cheah PY, 2016. Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review. Malar J 15: 523.
Adhikari B, Pell C, Phommasone K, Soundala X, Kommarasy P, Pongvongsa T, Henriques G, Day NPJ, Mayxay M, Cheah PY, 2017. Elements of effective community engagement: lessons from a targeted malaria elimination study in Lao PDR (Laos). Glob Health Action 10: 1366136.
Adhikari B 2017. Factors associated with population coverage of targeted malaria elimination (TME) in southern Savannakhet Province, Lao PDR. Malar J 16: 424.
von Seidlein L, Dondorp A, 2015. Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance. Expert Rev Anti Infect Ther 13: 715–730.