We would like to thank the State and Local Government Area Ministries of Health, including the field teams who made this study possible. We would also like to thank the village members who assisted us in village mobilization and organization, and the village members who participated in the study. We express our gratitude to Josephine Obiezu for her excellent and tireless data management. The study was funded by The Carter Center and the Sir Emeka Offor Foundation. The Bill and Melinda Gates Foundation and USAID supported LoaScope development.
Cupp EW, Sauerbrey M, Richards F, 2011. Elimination of human onchocerciasis: history of progress and current feasibility using ivermectin (Mectizan®) monotherapy. Acta Trop 120 (Suppl 1): S100–S108.
World Health Organization, 2017. Summary of global update on preventive chemotherapy implementation in 2016: crossing the billion. Wkly Epidemiol Rec 92: 589–593.
Diawara L et al. 2009. Feasibility of onchocerciasis elimination with ivermectin treatment in endemic foci in Africa: first evidence from studies in Mali and Senegal. PLoS Negl Trop Dis 3: e497.
Kelly-Hope LA, Unnasch TR, Stanton MC, Molyneux DH, 2015. Hypo-endemic onchocerciasis hotspots: defining areas of high risk through micro-mapping and environmental delineation. Infect Dis Poverty 4: 36.
Mectizan Donation Program, 1996. Central Nervous System (CNS) Complications of Loiasis and Adverse CNS Events Following Treatment: Report of an Invited Consultation. October 2–3, 1995, Atlanta, GA: Mectizan Donation Program.
Boussinesq M, Gardon J, 1997. Prevalences of Loa loa microfilaraemia throughout the area endemic for the infection. Ann Trop Med Parasitol 91: 573–589.
Boussinesq M, Gardon J, Gardon-Wendel N, Kamgno J, Ngoumou P, Chippaux JP, 1998. Three probable cases of Loa loa encephalopathy following ivermectin treatment for onchocerciasis. Am J Trop Med Hyg 58: 461–469.
Kamgno J, Boussinesq M, Labrousse F, Nkegoum B, Thylefors BI, Mackenzie CD, 2008. Encephalopathy after ivermectin treatment in a patient infected with Loa loa and Plasmodium spp. Am J Trop Med Hyg 78: 546–551.
Gardon J, Gardon-Wendel N, Demanga N, Kamgno J, Chippaux JP, Boussinesq M, 1997. Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection. Lancet 350: 18–22.
Addiss DG, Rheingans R, Twum-Danso NA, Richards FO, 2003. A framework for decision-making for mass distribution of Mectizan(R) in areas endemic for Loa loa. Filaria J 2 (Suppl 1): S9.
Twum-Danso NA, 2003. Loa loa encephalopathy temporally related to ivermectin administration reported from onchocerciasis mass treatment programs from 1989 to 2001: implications for the future. Filaria J 2 (Suppl 1): S7.
Diggle PJ et al. 2007. Spatial modelling and the prediction of Loa loa risk: decision making under uncertainty. Ann Trop Med Parasitol 101: 499–509.
Tekle AH, Zoure H, Wanji S, Leak S, Noma M, Remme JH, Amazigo U, 2011. Integrated rapid mapping of onchocerciasis and loiasis in the Democratic Republic of Congo: impact on control strategies. Acta Trop 120 (Suppl 1): S81–S90.
Wanji S, 2001. Rapid Assessment Procedures for Loiasis: Report of a Multi-centre Study. Geneva, Switzerland: UNDP/World Bank/World Health Organization Special Programme for Research & Training in Tropical Diseases.
Wanji S, Akotshi DO, Mutro MN, Tepage F, Ukety TO, Diggle PJ, Remme JH, 2012. Validation of the rapid assessment procedure for loiasis (RAPLOA) in the Democratic Republic of Congo. Parasit Vectors 5: 25.
Zoure HG, Wanji S, Noma M, Amazigo UV, Diggle PJ, Tekle AH, Remme JH, 2011. The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA). PLoS Negl Trop Dis 5: e1210.
D’Ambrosio MV et al. 2015. Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope. Sci Transl Med 7: 286re4.
Kamgno J, Pion SD, Mackenzie CD, Thylefors B, Boussinesq M, 2009. Loa loa microfilarial periodicity in ivermectin-treated patients: comparison between those developing and those free of serious adverse events. Am J Trop Med Hyg 81: 1056–1061.
Federal Ministry of Health, Nigeria, 2017. Nigeria Onchocerciasis Elimination Plan. Abuja, Nigeria: Federal Ministry of Health.
Takougang I et al. 2002. Rapid assessment method for prevalence and intensity of Loa loa infection. Bull World Health Organ 80: 852–858.
Hassan AA, Akinsanya B, Iyase N, Owagboriaye FO, 2011. Assessment of loiasis and outcomes of ivermectin masstreatment in Ijebu-North, Nigeria. Korean J Parasitol 49: 153–159.
Anonymous, 2016. Communiqué of the 5th Onchocerciasis Elimination Committee (NOEC). December 14–16, 2016, Barcelona Hotel, Abuja, Nigeria.
World Health Organization/Department of Control of Neglected Tropical Diseases, 2012. Provisional Strategy for Interrupting Lymphatic Filariasis Transmission in Loiasis-endemic Countries: Report of the Meeting on Lymphatic Filariasis, Malaria and Integrated Vector Management. Accra, Ghana: WHO.