The Treatment of Enterobiasis in Children. A Comparative Study of Piperazine (Antepar) and Pyrvinium Chloride (Vanquin)

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  • Department of Pediatrics, School of Medicine, University of Buffalo, and Edward J. Meyer Memorial Hospital, Buffalo, New York

Summary

Results of treatment of enterobiasis in children with two efficient oxyuricides are reported. The percentage of cures in a group of 34 infected children treated with a single daily dose of 3 gm of piperazine for 3 days was 90.6 per cent. The cure rate among 34 infected children treated with a single daily dose of 3 gm of piperazine for 2 days was 86.2 per cent. The cure rate among 35 infected children treated with 1.5 mg/kg of pyrvinium chloride daily for 6 days was 100 per cent. The cure rate among 36 infected children treated with 2.1 mg/kg of pyrvinium chloride daily for 6 days was 97.1 per cent.

Both piperazine and pyrvinium chloride were well accepted and tolerated, and no untoward or toxic reactions were experienced by any of the children.

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