The Treatment of Enterobiasis in Children. A Comparative Study of Piperazine (Antepar) and Pyrvinium Chloride (Vanquin)
Summary
Results of treatment of enterobiasis in children with two efficient oxyuricides are reported. The percentage of cures in a group of 34 infected children treated with a single daily dose of 3 gm of piperazine for 3 days was 90.6 per cent. The cure rate among 34 infected children treated with a single daily dose of 3 gm of piperazine for 2 days was 86.2 per cent. The cure rate among 35 infected children treated with 1.5 mg/kg of pyrvinium chloride daily for 6 days was 100 per cent. The cure rate among 36 infected children treated with 2.1 mg/kg of pyrvinium chloride daily for 6 days was 97.1 per cent.
Both piperazine and pyrvinium chloride were well accepted and tolerated, and no untoward or toxic reactions were experienced by any of the children.