Scrub typhus in Japan: epidemiology and clinical features of cases reported in 1998.

Motohiko OgawaDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Motohiko Ogawa in
Current site
Google Scholar
PubMed
Close
,
Toshikatsu HagiwaraDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Toshikatsu Hagiwara in
Current site
Google Scholar
PubMed
Close
,
Toshio KishimotoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Toshio Kishimoto in
Current site
Google Scholar
PubMed
Close
,
Sadashi ShigaDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Sadashi Shiga in
Current site
Google Scholar
PubMed
Close
,
Yoshiya YoshidaDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Yoshiya Yoshida in
Current site
Google Scholar
PubMed
Close
,
Yumiko FuruyaDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Yumiko Furuya in
Current site
Google Scholar
PubMed
Close
,
Ikuo KaihoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Ikuo Kaiho in
Current site
Google Scholar
PubMed
Close
,
Tadahiko ItoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Tadahiko Ito in
Current site
Google Scholar
PubMed
Close
,
Haruyasu NemotoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Haruyasu Nemoto in
Current site
Google Scholar
PubMed
Close
,
Norishige YamamotoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Norishige Yamamoto in
Current site
Google Scholar
PubMed
Close
, and
Kunihiko MasukawaDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ogawam@nih.go.jp

Search for other papers by Kunihiko Masukawa in
Current site
Google Scholar
PubMed
Close

Surveillance for scrub typhus was conducted in Japan in 1998 using a questionnaire. A total of 462 cases were reported. Scrub typhus occurred in both the fall and spring in the northern part of Honshu (the main island), and in the fall in the central part of Honshu and on the island of Kyushu. The occurrence of the disease varied with age, gender, and activity. Seventy-six percent of the patients were more than 51 years old, and 36% and 16% of the patients were engaged in farm work and forestry, respectively. Fever, rash, and eschar were detected in 98%, 93%, and 97% of the patients, respectively. Elevated levels of C-reactive protein, aspartate transaminase, and alanine transaminase were detected in 96%, 87%, and 77% of the patients, respectively. Disseminated intravascular coagulation developed in 34 cases and had a unique regional distribution. This study shows the status of scrub typhus in Japan in 1998 and provides important information for diagnosis and prevention.

Save