The Anthelmintic Effect of Dithiazanine in Experimental Animals

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  • Lilly Research Laboratories, Indianapolis, Indiana


A new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.

Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.