This site uses cookies, tags, and tracking settings to store information that help give you the very best browsing experience. Dismiss this warning

Short Report: Diminished Susceptibility to Praziquantel in a Senegal Isolate of Schistosoma mansoni

P. G. Fallon School of Biological Sciences, University of Wales, Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Service Regional de St. Louis, Bangor, Gwynedd, United Kingdom

Search for other papers by P. G. Fallon in
Current site
Google Scholar
PubMed Close
,
R. F. Sturrock School of Biological Sciences, University of Wales, Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Service Regional de St. Louis, Bangor, Gwynedd, United Kingdom

Search for other papers by R. F. Sturrock in
Current site
Google Scholar
PubMed Close
,
A. Capron School of Biological Sciences, University of Wales, Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Service Regional de St. Louis, Bangor, Gwynedd, United Kingdom

Search for other papers by A. Capron in
Current site
Google Scholar
PubMed Close
,
M. Niang School of Biological Sciences, University of Wales, Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Service Regional de St. Louis, Bangor, Gwynedd, United Kingdom

Search for other papers by M. Niang in
Current site
Google Scholar
PubMed Close
, and
M. J. Doenhoff School of Biological Sciences, University of Wales, Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Service Regional de St. Louis, Bangor, Gwynedd, United Kingdom

Search for other papers by M. J. Doenhoff in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.1995.53.61
Volume/Issue:
Volume 53: Issue 1
Page(s):
61–62
Restricted access
Get Permissions

There is a recent report of low efficacy of praziquantel (PZQ) treatment of human schistosomiasis in a new Schistosoma mansoni focus in northern Senegal. Biomphalaria pfeifferi snails with patent infections were collected from the area of the focus and transported to the United Kingdom. Groups of mice were infected with cercariae from this Senegalese isolate, or with laboratory-maintained Kenyan or Puerto Rican isolates. In two separate experiments, PZQ was less effective against the parasite from Senegal than against the two other geographic isolates. The reduced susceptibility of S. mansoni to PZQ in infected human populations has important implications for current schistosomiasis control programs.

Author Notes

Copyright:
Copyright © 1995 by The American Society of Tropical Medicine and Hygiene 1995
Published Online:
Jul 1995
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Ahead of Print
Volume: 112 (2025)
Show Items
Volume: 111 (2024)
Show Items
Volume: 110 (2024)
Show Items
Volume: 109 (2023)
Show Items
Volume: 108 (2023)
Show Items
Volume: 107 (2022)
Show Items
Volume: 106 (2022)
Show Items
Volume: 105 (2021)
Show Items
Volume: 104 (2021)
Show Items
Volume: 103 (2020)
Show Items
Volume: 102 (2020)
Show Items
Volume: 101 (2019)
Show Items
Volume: 100 (2019)
Show Items
Volume: 99 (2018)
Show Items
Volume: 98 (2018)
Show Items
Volume: 97 (2017)
Show Items
Volume: 96 (2017)
Show Items
Volume: 95 (2016)
Show Items
Volume: 94 (2016)
Show Items
Volume: 93 (2015)
Show Items
Volume: 92 (2015)
Show Items
Volume: 91 (2014)
Show Items
Volume: 90 (2014)
Show Items
Volume: 89 (2013)
Show Items
Volume: 88 (2013)
Show Items
Volume: 87 (2012)
Show Items
Volume: 86 (2012)
Show Items
Volume: 85 (2011)
Show Items
Volume: 84 (2011)
Show Items
Volume: 83 (2010)
Show Items
Volume: 82 (2010)
Show Items
Volume: 81 (2009)
Show Items
Volume: 80 (2009)
Show Items
Volume: 79 (2008)
Show Items
Volume: 78 (2008)
Show Items
Volume: 77 (2007)
Show Items
Volume: 76 (2007)
Show Items
Volume: 75 (2006)
Show Items
Volume: 74 (2006)
Show Items
Volume: 73 (2005)
Show Items
Volume: 72 (2005)
Show Items
Volume: 71 (2004)
Show Items
Volume: 70 (2004)
Show Items
Volume: 69 (2003)
Show Items
Volume: 68 (2003)
Show Items
Volume: 67 (2002)
Show Items
Volume: 66 (2002)
Show Items
Volume: 65 (2001)
Show Items
Volume: 64 (2001)
Show Items
Volume: 63 (2000)
Show Items
Volume: 62 (2000)
Show Items
Volume: 61 (1999)
Show Items
Volume: 60 (1999)
Show Items
Volume: 59 (1998)
Show Items
Volume: 58 (1998)
Show Items
Volume: 57 (1997)
Show Items
Volume: 56 (1997)
Show Items
Volume: 55 (1996)
Show Items
Volume: 54 (1996)
Show Items
Volume: 53 (1995)
Show Items
Volume: 52 (1995)
Show Items
Volume: 51 (1994)
Show Items
Volume: 50 (1994)
Show Items
Volume: 49 (1993)
Show Items
Volume: 48 (1993)
Show Items
Volume: 47 (1992)
Show Items
Volume: 46 (1992)
Show Items
Volume: 45 (1991)
Show Items
Volume: 44 (1991)
Show Items
Volume: 43 (1990)
Show Items
Volume: 42 (1990)
Show Items
Volume: 41 (1989)
Show Items
Volume: 40 (1989)
Show Items
Volume: 39 (1988)
Show Items
Volume: 38 (1988)
Show Items
Volume: 37 (1987)
Show Items
Volume: 36 (1987)
Show Items
Volume: 35 (1986)
Show Items
Volume: 34 (1985)
Show Items
Volume: 33 (1984)
Show Items
Volume: 32 (1983)
Show Items
Volume: 31 (1982)
Show Items
Volume: 30 (1981)
Show Items
Volume: 29 (1980)
Show Items
Volume: 28 (1979)
Show Items
Volume: 27 (1978)
Show Items
Volume: 26 (1977)
Show Items
Volume: 25 (1976)
Show Items
Volume: 24 (1975)
Show Items
Volume: 23 (1974)
Show Items
Volume: 22 (1973)
Show Items
Volume: 21 (1972)
Show Items
Volume: 20 (1971)
Show Items
Volume: 19 (1970)
Show Items
Volume: 18 (1969)
Show Items
Volume: 17 (1968)
Show Items
Volume: 16 (1967)
Show Items
Volume: 15 (1966)
Show Items
Volume: 14 (1965)
Show Items
Volume: 13 (1964)
Show Items
Volume: 12 (1963)
Show Items
Volume: 11 (1962)
Show Items
Volume: 10 (1961)
Show Items
Volume: 9 (1960)
Show Items
Volume: 8 (1959)
Show Items
Volume: 7 (1958)
Show Items
Volume: 6 (1957)
Show Items
Volume: 5 (1956)
Show Items
Volume: 4 (1955)
Show Items
Volume: 3 (1954)
Show Items
Volume: 2 (1953)
Show Items
Volume: 1 (1952)
Show Items
Volume: s1-31 (1951)
Show Items
Volume: s1-30 (1950)
Show Items
Volume: s1-29 (1949)
Show Items
Volume: s1-28 (1948)
Show Items
Volume: s1-27 (1947)
Show Items
Volume: s1-26 (1946)
Show Items
Volume: s1-25 (1945)
Show Items
Volume: s1-24 (1944)
Show Items
Volume: s1-23 (1943)
Show Items
Volume: s1-22 (1942)
Show Items
Volume: s1-21 (1941)
Show Items
Volume: s1-20 (1940)
Show Items
Volume: s1-19 (1939)
Show Items
Volume: s1-18 (1938)
Show Items
Volume: s1-17 (1937)
Show Items
Volume: s1-16 (1936)
Show Items
Volume: s1-15 (1935)
Show Items
Volume: s1-14 (1934)
Show Items
Volume: s1-13 (1933)
Show Items
Volume: s1-12 (1932)
Show Items
Volume: s1-11 (1931)
Show Items
Volume: s1-10 (1930)
Show Items
Volume: s1-9 (1929)
Show Items
Volume: s1-8 (1928)
Show Items
Volume: s1-7 (1927)
Show Items
Volume: s1-6 (1926)
Show Items
Volume: s1-5 (1925)
Show Items
Volume: s1-4 (1924)
Show Items
Volume: s1-3 (1923)
Show Items
Volume: s1-2 (1922)
Show Items
Volume: s1-1 (1921)
Show Items
Past two years Past Year Past 30 Days
Abstract Views 845 271 56
Full Text Views 19 1 0
PDF Downloads 19 2 0
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save