Trypanosoma Cruzi: Antigenic Analysis of Cloned Stocks

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  • Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20205

The antigenic constitution of two Trypanosoma cruzi strains and six cloned stocks was determined immunoelectrophoretically. Five to seven antigens common to all of the T. cruzi stocks were found. However, each stock also contained “strain-specific antigens,” and five of the six cloned stocks presented “clone-specific antigens.” These data demonstrate that a T. cruzi strain is composed of an antigenically heterogeneous population of organisms.

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