Combined Chloroquine/Fansidar®-Resistant Falciparum Malaria Appears in East Africa

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  • Kilimanjaro Christian Medical Centre, Tanzania Consultant Hospital, Moshi, Tanzania, East Africa

The first two cases from East Africa of RII chloroquine- and Fansidar®-resistant falciparum malaria are described. The first case occurred in a non-immune Swedish expatriate 2 weeks after arrival in Tanzania, and the second in a semi-immune Tanzanian soldier. Fansidar has not yet been marketed in Tanzania. The significance and etiology of the occurrence of combined chloroquine/Fansidar resistance in East Africa are discussed.

Author Notes

Present address: % Internal Department, Elisabeth's Gasthuis, Boerhaavelaan 22, 2035 RC Haarlem, The Netherlands.