Treatment of naturally acquired scrub typhus due to the Pescadores strains of Rickettsia orientalis can be successfully accomplished with chloramphenicol, aureomycin and terramycin. A total dose of 5.0 to 6.0 grams of any of these drugs administered orally in two doses within 12 to 24 hours will control the disease in the majority of the cases. Relapses tend to be more frequent in those treated early, but are controlled with doses of 4.0 to 5.0 grams of drug. The Malayan and Pescadores strains of Rickettsia orientalis are closely similar in their clinical response to these antibiotics.
Present address: Milwaukee County Hospital, Milwaukee 13, Wisconsin.
National Defense Medical Center, Taipei, Taiwan.
Cdr. and Officer-in-charge, Fleet Epidemic Disease Control Unit Two.