Ten Clinical Cases of Human Infection with Venezuelan Equine Encephalomyelitis Virus, Subtype I-D

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  • Gorgas Memorial Institute—Middle America Research Unit, Box 2011, Balboa Heights, Canal Zone, Panama

The clinical and laboratory findings in ten humans infected with Venezuelan equine encephalitis virus, subtype I-D, are described in this report. Clinical and laboratory data indicate that, in contrast to equine infections, human infection with these enzootic virus strains (I-D) is similar to human infection with epizootic strains (I-ABC). In most cases there was an abrupt onset of fever, muscle pain, and vomiting. Virus was recovered from sera obtained during the first 3 days of illness. Lymphopenia occurred in all patients, and neutropenia occurred in three. No sequelae of these infections were apparent.

Author Notes

Present address: Department of Nutrition and Food Science, MIT, 50 Ames Street, Cambridge, Massachusetts 02142.

Present address: Gorgas Memorial Laboratory, Box 2016, Balboa Heights, Canal Zone, Panama.

Present address: Center for Disease Control, Atlanta, Georgia 30333.