Hepatitis-Associated (Australia) Antigen in Nigerians

An Ultrastructural Study

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  • Department of Pathology, University of Ibadan, Department of Virology, Royal Postgraduate Medical School, Ibadan, Nigeria
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A series of Australia antigen-positive sera from healthy Nigerians was examined using the electron microscope. One serum was outstanding inasmuch as it contained a vast preponderance of the large 420 A Dane particles. Other sera exhibited the appearance accepted as the usual one in Australia antigen-positive sera. The significance of this variation in proportion of antigen forms is discussed and it is suggested that variations of this type could be of importance in prognosis.