Cache Valley Virus in the Del Mar Va Peninsula

I. Virologic and Serologic Evidence of Infection

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  • Departments of Virus Diseases and Entomology, Walter Reed Army Institute of Research, Department of Veterinary Science, University of Maryland, Wildlife Disease Laboratory, Patuxent Wildlife Research Center, U. S. Fish and Wildlife Service, Washington

An arthropod-borne virus, shown to be a member of the Bunyamwera group and closely related to Cache Valley virus, was recovered 12 times from salt-marsh mosquitoes collected from off-shore Virginia Islands between 1961 and 1964. Mosquito infection was detected only during August–October, even though search for mosquito infection was made annually during spring–summer. Most frequently infected mosquito species were Aedes sollicitans and Aedes taeniorhynchus. Serologic surveys were made to identify the natural hosts of this virus in and near the study sites. Few if any of small wild vertebrates (rodents, carnivores, birds, etc.) were found to possess serum neutralizing antibody. On the other hand, antibody was frequently found in serum of large vertebrates of the area, including cattle, horses, and man, and in these species, antibody prevalence was highest in residents of coastal areas.

Author Notes

Present address: Research Reference Reagents Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.


Present address: Department of Entomology, SEATO Medical Research Laboratory, Bangkok, Thailand.

‖Present address: Department of Pediatrics, Up-state Medical Center, University of Syracuse, Syracuse, New York.

Present address: Department of Veterinary Science, University of Wisconsin, Madison.