Intestinal Amebiasis

A Preliminary Clinical Trial of Furamide T/c

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  • Health Unit, Ministry of Health, Desamparados, San José, Costa Rica

Summary

Furamide® T/c, a combination of diloxanide furoate, tetracycline hydrochloride, and chloroquine phosphate, was tested under conditions of poor sanitation in 50 patients with intestinal protozoal infections. There was a follow-up period of 90 days after termination of therapy.

The combination was active against eight species of intestinal ameba and flagellate, clearing the stools, in most cases, within 48 hours of cessation of treatment, of both cysts and trophozoites.

Long-term investigations of this combination are warranted.

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