A modified radioactive rose bengal test is described which permits obtaining simultaneously data about the pulmonary circulation time, cardioportal circulation time and liver cell function.
This test was applied to 15 normal subjects and 61 patients suffering from hepatosplenic bilharziasis of variable severity. The results obtained confirm the rather late appearance of liver cell dysfunction in bilharziasis. This began to be seen in patients with firm livers even in the absence of signs of portal hypertension. The incidence of hepatocellular affection increased markedly with the appearance of esophageal varices and/or ascites.
Furthermore, the suggested test was of great value in cases of hepatosplenic affection with an associated cardiac lesion.
Head of Unit for Medical Research, A. E. E., U. A. R. Present address: 16 El Nil Street, Gizah, U. A. R.