Eastern Equine Encephalitis: Report of a Case with Autopsy

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Summary

This report deals with the clinical course and findings in a single patient with rapidly fatal viral encephalitis, complicated by an angiomatous malformation of the cerebellum. Histologic examination revealed vascular, glial, and neuronal lesions in both the cerebrum and cerebellum.

Virus isolation studies were performed on tissue obtained at autopsy proving the infectious agent to be of the Eastern equine group. The pertinent literature is briefly reviewed.

No definite conclusions are presently justifiable with regard to the causal relationship of encephalitis and vascular malformation of the brain.

Author Notes

Resident in Pathology, U. S. Public Health Service Hospital, Baltimore, Maryland. Present address: Pathology Service, U. S. Public Health Service Hospital, 77 Warren Street, Boston (Brighton), Massachusetts.

Professor of Neuropathology, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland.

Director and Head, Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.

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