Chloroquine-Resistant Strain of Plasmodium Falciparum from Khao Mai Khaeo, Thailand

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  • Malaria Research Project, U. S. Component, SEATO Medical Research Laboratory, APO 146, San Francisco, California


A naturally infected case of chloroquine-pyrimethamine resistant Plasmodium falciparum malaria acquired in Khao Mai Khaeo, Cholburi Province, Thailand, is described. This strain of P. falciparum was inoculated into a healthy volunteer. The artificially induced infection also proved to be resistant to chloroquine and pyrimethamine. Radical cure was effected by quinine therapy.

Author Notes

Malariologist, Malaria Research Project.

Biochemist, Malaria Research Project.

1st Lt., MSC, Assistant Chief, Department of Medical Entomology.