We acknowledge the kind gift of recombinant SE36 and mouse polyclonal antisera against SE36 by Professor Toshihori Horii, Osaka University; Research Institute for Microbial Diseases (RIMD), Osaka; and the technical support by veterinarians and animal technicians at the Institute of Primate Research, Nairobi, Kenya.
Ceesay SJ et al. 2015. Malaria prevalence among young infants in different transmission settings, Africa. Emerg Infect Dis 21: 1114–1121.
Mbonye MK , Burnett SM , Naikoba S , Colebunders R , Wouters K , Weaver MR , Van Geertruyden JP , 2015. Malaria care in infants aged under six months in Uganda: an area of unmet needs! PLoS One 10: e0123283.
Fairhurst RM , Dondorp AM , 2016. Artemisinin-resistant Plasmodium falciparum malaria. Scheld W , Hughes J , Whitley R (eds), Emerging Infections 10. Washington, DC: ASM Press, 409–429.
Mulamba C , Riveron JM , Ibrahim SS , Irving H , Barnes KG , Mukwaya LG , Birungi J , Wondji CS , 2014. Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PLoS One 9: e110058.
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Mulamba C Riveron JM Ibrahim SS Irving H Barnes KG Mukwaya LG Birungi J Wondji CS 2014. Widespread pyrethroid and DDT resistance in the major malaria vector. PLoS One Anopheles funestusin East Africa is driven by metabolic resistance mechanisms 9: e110058.
RTS,S Clinical Trials Partnership Agnandji ST et al. 2012. A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N Engl J Med 367: 2284–2295.
Van den Berg M , Ogutu B , Sewankambo NK , Biller-Andorno N , Tanner M , 2019. RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials. Trials 20: 316.
Barrios C , 1996. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting. Eur J Immunol 26: 1489–1496.
Black A , Bhaumik S , Kirkman RL , Weaver CT , Randolph DA , 2012. Developmental regulation of Th17-cell capacity in human neonates. Eur J Immunol 42: 311–319.
Siegrist CA , 2003. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine 21: 3406–3412.
Mosconi E et al. 2010. Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol 3: 461–474.
van den Elsen LWJ , Verhasselt V , Egwang T , 2020. Malaria antigen shedding in the breast milk of mothers from a region with endemic malaria. JAMA Pediatr 174: 297–298.
Palacpac NMQ et al. 2013. Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36. PLoS One 8: e64073.
Sirima S , Tiono AB , Houard S , Bougouma EC , Coulibaly SA , Leroy O , Palacpac N , Horii T , Ouedraogo IN , 2019. OC 8546 safety and immunogenicity of the malaria vaccine candidate BK-SE36 in young children living in Burkina Faso. BMJ Glob Health 4: A12–A13.
Verhasselt V , Milcent V , Cazareth J , Kanda A , Fleury S , Dombrowicz D , Glaichenhaus N , Julia V , 2008. Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma. Nat Med 14: 170–175.
Willingham K , McNulty E , Anderson K , Hayes-Klug J , Nalls A , Mathiason C , 2014. Milk collection methods for mice and Reeves’ muntjac deer. J Vis Exp 89: 51007.
Field CJ , 2005. The immunological components of human milk and their effect on immune development in infants. J Nutr 135: 1–4.
MacDougall DM , Halperin SA , 2016. Improving rates of maternal immunization: challenges and opportunities. Hum Vaccin Immunother 12: 857–865.