• 1.

    Flick R, Whitehouse CA, 2005. Crimean-Congo hemorrhagic fever virus. Curr Mol Med 5: 753760.

  • 2.

    Fillâtre P, Revest M, Tattevin P, 2019. Crimean-Congo hemorrhagic fever: an update. Med Mal Infect 49: 574585.

  • 3.

    Ergönül Ö, 2006. Crimean-Congo haemorrhagic fever. Lancet Infect Dis 6: 203214.

  • 4.

    Ergonul O, 2008. Treatment of Crimean-Congo hemorrhagic fever. Antiviral Res 78: 125131.

  • 5.

    Connolly-Andersen AM, Moll G, Andersson C, Åkerström S, Karlberg H, Douagi I, Mirazimi A, 2011. Crimean-Congo hemorrhagic fever virus activates endothelial cells. J Virol 85: 77667774.

    • Search Google Scholar
    • Export Citation
  • 6.

    Yilmaz G, Koksal I, Topbas M, Yilmaz H, Aksoy F, 2010. The effectiveness of routine laboratory findings in determining disease severity in patients with Crimean-Congo hemorrhagic fever: severity prediction criteria. J Clin Virol 47: 361365.

    • Search Google Scholar
    • Export Citation
  • 7.

    Swanepoel R, Gill D, Shepherd A, Leman P, Mynhardt J, Harvey S, 1989. The clinical pathology of Crimean-Congo hemorrhagic fever. Rev Infect Dis 11: S794S800.

    • Search Google Scholar
    • Export Citation
  • 8.

    Ergönül Ö, Çelikbaş A, Dokuzoğuz B, Eren Ş, Baykam N, Esener H, 2004. Characteristics of patients with Crimean-Congo hemorrhagic fever in a recent outbreak in Turkey and impact of oral ribavirin therapy. Clin Infect Dis 39: 284287.

    • Search Google Scholar
    • Export Citation
  • 9.

    Başekim C, Kizilkaya E, Pekkafali Z, Baykal K, Karsli A, 2000. Mumps epididymo-orchitis: sonography and color doppler sonographic findings. Abdom Imaging 25: 322325.

    • Search Google Scholar
    • Export Citation
  • 10.

    Jalal H, Bahadur G, Knowles W, Jin L, Brink N, 2004. Mumps epididymo‐orchitis with prolonged detection of virus in semen and the development of anti‐sperm antibodies. J Med Virol 73: 147150.

    • Search Google Scholar
    • Export Citation
  • 11.

    Aksoy HZ, Yilmaz G, Aksoy F, Koksal I, 2010. Crimean-Congo haemorrhagic fever presenting as epididymo-orchitis. J Clin Virol 48: 282284.

 

 

 

 

Case Report: A Rare Case of Crimean–Congo Hemorrhagic Fever Associated with Epididymo-Orchitis

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  • 1 Depertmant of Infection Diseases and Clinical Microbiology, Health Sciences University, Erzurum Regional Education and Research Hospital, Erzurum, Turkey;
  • 2 Depertmant of Urology, Health Sciences University Erzurum Regional Education and Research Hospital, Erzurum, Turkey;
  • 3 Depertmant of Pulmonology, Ataturk University, Erzurum, Turkey

ABSTRACT

Crimean–Congo hemorrhagic fever (CCHF) is an acute infectious disease that affects multiple organ systems and is characterized by extensive ecchymosis, internal hemorrhage, and hepatic dysfunction. The reported case fatality rate varies between 8% and 80%. It is frequently transmitted by Hyalomma ticks, which are endemic in the Northeast Anatolia region of Turkey in spring and summer. Our patient presented from an endemic area with fever, malaise, joint pain, and scrotal pain following a tick bite, and real-time PCR analysis of venous blood was positive for CCHF. Based on Doppler ultrasound performed because of the patient’s scrotal pain, he was diagnosed as having epididymo-orchitis, which was considered secondary to CCHF after ruling out other etiologies and resolved with scrotal elevation and anti-inflammatory treatment. Being a very rare complication, this report aimed to document this case of CCHF-associated epididymo-orchitis in the literature.

Author Notes

Address correspondence to Ferhan Kerget, Infection Diseases and Clinical Microbiology, Health Sciences Unversity, Çat Rd. St., Erzurum 25240, Turkey. E-mail: drferhan68@hotmail.com

Authors’ addresses: Ferhan Kerget, Depertmant of Infection Diseases and Clinical Microbiology, Erzurum Bölge Eğitim ve Araştırma Hastanesi, Erzurum, Turkey, E-mail: drferhan68@hotmail.com. Şaban Oğuz Demirdöğen, Depertmant of Urology, Erzurum Bolge Egitim ve Arastirma Hastanesi, Erzurum, Turkey, E-mail: oguzdemirdogen@hotmail.com. Buğra Kerget, Depertmant of Pulmonology, Ataturk Universitesi, Erzurum, Turkey, E-mail: bjkerget1903@gmail.com.

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