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Images in Clinical Tropical Medicine

Water Bottle–Shaped Heart in a Five-Year-Old Boy

B. Jason Brotherton Department of Internal Medicine, AIC Kijabe Hospital, Kijabe, Kenya;
Department of Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya;

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Esther W. Kimani-Mangoli Department of Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya;

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Arianna McLain Shirk Department of Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya;
University of Alabama Birmingham, Birmingham, Alabama

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DOI:
https://doi.org/10.4269/ajtmh.18-0956
Volume/Issue:
Volume 101: Issue 1
Page(s):
3–4
Open access
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A 5-year-old previously healthy Somali boy presented to our mission hospital in rural Kenya with a 2 week history of a gradual onset of fever, chest discomfort, and difficulty in breathing, accompanied by nonproductive cough, easy fatiguability, and loss of appetite.

Vital signs were as follows: temperature 39.6°C, heart rate 105, respiratory rate 40, oxygen saturation 92% on room air, and weight 13 kg with a mid-upper arm circumference of 11.5 (indicating severe malnutrition). Physical examination was notable for a thin, ill-appearing boy sitting upright in bed. Heart sounds were muffled; peripheral pulses were full. Breath sounds were clear despite being tachypneic. The rest of his physical examination was normal for age.

Laboratory investigations were significant for a white blood cell count of 32,300 mm3 (75% granulocytes, 14% lymphocytes, and 11% monocytes), hemoglobin 8.2 g/dL, and platelets 393,000/mm3. Testing for HIV by rapid antigen test and for tuberculosis (TB) via GeneXpert of a gastric aspirate was negative. Chest radiograph showed an enlarged, globular cardiac silhouette (Figure 1) with unremarkable lung fields. Bedside echocardiography showed good contractility, normal appearing valves, and a moderate pericardial effusion with extensive fibrinous exudate (arrow) extending from the pericardium to the epicardium (Figure 2). A clinical diagnosis of extrapulmonary TB with tuberculous pericarditis was made.

Figure 1.
Figure 1.

Chest radiograph showing water bottle shaped heart.

Citation: The American Journal of Tropical Medicine and Hygiene 101, 1; 10.4269/ajtmh.18-0956

Figure 2.
Figure 2.

Parasternal long axis view showing moderate pericardial effusion and fibrinous exudate (arrow).

Citation: The American Journal of Tropical Medicine and Hygiene 101, 1; 10.4269/ajtmh.18-0956

Pericarditis is a well-known extrapulmonary manifestation of TB and the most common cause of pericardial effusion in the resource-limited setting.1 Despite this boy having the classic water bottle appearance to the cardiac silhouette, radiography has low sensitivity for detecting pericardial effusion.2 Echocardiogram is the definitive test to confirm the presence of pericardial effusion, especially when fibrinous material is observed.

He was started on four drug anti-TB regimen and prednisone 2 mg/kg for the pericardial effusion. A Cochrane review from 2017 suggested that HIV-negative individuals with TB pericarditis may have reduced incidence of death if treated with corticosteroids.3

Repeat echocardiogram after 14 days of therapy showed near complete resolution of the effusion (Figure 3). He was discharged on day 22 of hospitalization.

Figure 3.
Figure 3.

Repeat parasternal long axis view showing resolution of pericardial effusion.

Citation: The American Journal of Tropical Medicine and Hygiene 101, 1; 10.4269/ajtmh.18-0956

REFERENCES

  • 1.↑

    Obihara NJ, Walters E, Lawrenson J, Garcia-Prats AJ, Hesseling AC, Schaaf HS, 2017. Tuberculous pericardial effusions in children. J Pediatric Infect Dis Soc 22: 1–4.

  • 2.↑

    Eisenberg MJ, Dunn MM, Kanth N, Gamsu G, Schiller NB, 1993. Diagnostic value of chest radiography for pericardial effusion. J Am Coll Cardiol 22: 588–593.

  • 3.↑

    Wiysonge CS, Ntsekhe M, Thabane L, Volmink J, Majombozi D, Gumedze F, Pandie S, Mayosi BM, 2017. Interventions for treating tuberculous pericarditis. Cochrane Database Syst Rev 9: CD000526.

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Author Notes

Address correspondence to B. Jason Brotherton, AIC Kijabe Hospital, P.O. Box 20, Kijabe 00220, Kenya. E-mail: jb042107@gmail.com

Authors’ addresses: B. Jason Brotherton, Departments of Internal Medicine and Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya, E-mail: jb042107@gmail.com. Esther W. Kimani-Mangoli, Department of Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya, E-mail: drekimani@gmail.com. Arianna McLain Shirk, University of Alabama Birmingham, Birmingham, AL, and Department of Paediatrics, AIC Kijabe Hospital, Kijabe, Kenya, E-mail: ashirk@gmail.com.

Copyright:
© The American Society of Tropical Medicine and Hygiene 2019
Received:
03 Dec 2018
|
Accepted:
11 Feb 2019
|
Published Online:
03 Jul 2019
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Online ISSN:
1476-1645
  • Figure 1.
    View in gallery
    Figure 1.

    Chest radiograph showing water bottle shaped heart.

  • Figure 2.
    View in gallery
    Figure 2.

    Parasternal long axis view showing moderate pericardial effusion and fibrinous exudate (arrow).

  • Figure 3.
    View in gallery
    Figure 3.

    Repeat parasternal long axis view showing resolution of pericardial effusion.

Figure 1.

Chest radiograph showing water bottle shaped heart.
Figure 2.

Parasternal long axis view showing moderate pericardial effusion and fibrinous exudate (arrow).
Figure 3.

Repeat parasternal long axis view showing resolution of pericardial effusion.
  • 1.

    Obihara NJ, Walters E, Lawrenson J, Garcia-Prats AJ, Hesseling AC, Schaaf HS, 2017. Tuberculous pericardial effusions in children. J Pediatric Infect Dis Soc 22: 1–4.

  • 2.

    Eisenberg MJ, Dunn MM, Kanth N, Gamsu G, Schiller NB, 1993. Diagnostic value of chest radiography for pericardial effusion. J Am Coll Cardiol 22: 588–593.

  • 3.

    Wiysonge CS, Ntsekhe M, Thabane L, Volmink J, Majombozi D, Gumedze F, Pandie S, Mayosi BM, 2017. Interventions for treating tuberculous pericarditis. Cochrane Database Syst Rev 9: CD000526.

    • PubMed
    • Search Google Scholar
    • Export Citation
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