Volume 99, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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The Potential for Testing Stool to Reduce Tuberculosis Missed Diagnoses and Misdiagnoses, Page 1 of 1

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  1. Evans CA, , 2011. GeneXpert—a game-changer for tuberculosis control? PLoS Med 8: e1001064.
  2. McCarthy K, Fielding K, Churchyard GJ, Grant AD, , 2018. Empiric tuberculosis treatment in South African primary health care facilities—for whom, where, when and why: implications for the development of tuberculosis diagnostic tests. PLoS One 13: e0191608.
  3. Wingfield T, Boccia D, Tovar M, Gavino A, Zevallos K, Montoya R, Lönnroth K, Evans CA, , 2014. Defining catastrophic costs and comparing their importance for adverse tuberculosis outcome with multi-drug resistance: a prospective cohort study, Peru. PLoS Med 11: e1001675.
  4. Martinson NA, Karstaedt A, Venter WF, Omar T, King P, Mbengo T, Marais E, McIntyre J, Chaisson R, Hale M, , 2007. Causes of death in hospitalized adults with a premortem diagnosis of tuberculosis: an autopsy study. AIDS 21: 20432050.
  5. Moore DAJ, 2006. Microscopic-observation drug-susceptibility assay for the diagnosis of TB. N Engl J Med 355: 15391550.
  6. DiNardo AR, 2018. Diagnostic and treatment monitoring potential of a stool-based quantitative PCR assay for pulmonary tuberculosis. Am J Trop Med Hyg 99: 310316, doi:10.4269/ajtmh.18-0004.
  7. Oberhelman RA, 2015. A controlled study of tuberculosis diagnosis in HIV-infected and uninfected children in Peru. PLoS One 10: e0120915.
  8. Burman WJ, Reves RR, , 2000. Review of false-positive cultures for Mycobacterium tuberculosis and recommendations for avoiding unnecessary treatment. Clin Infect Dis 31: 13901395.
  9. de Boer AS, Blommerde B, de Haas PEW, Sebek MMGG, Lambregts-van Weezenbeek KSB, Dessens M, van Soolingen D, , 2002. False-positive Mycobacterium tuberculosis cultures in 44 laboratories in The Netherlands (1993 to 2000): incidence, risk factors, and consequences. J Clin Microbiol 40: 40044009.
  10. Steingart KR, Schiller I, Horne DJ, Pai M, Boehme CC, Dendukuri N, , 2014. Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev 1: CD009593.
  11. Mayta H, 2003. Evaluation of a PCR-based universal heteroduplex generator assay as a tool for rapid detection of multidrug-resistant Mycobacterium tuberculosis in Peru. J Clin Microbiol 41: 57745777.
  12. Datta S, Shah L, Gilman RH, Evans CA, , 2017. Comparison of sputum collection methods for tuberculosis diagnosis: a systematic review and pairwise and network meta-analysis. Lancet Glob Health 5: e760e771.
  13. Chow F, Espiritu N, Gilman RH, Gutierrez R, Lopez S, Escombe AR, Evans CAW, Moore DAJ, , 2006. La cuerda dulce—a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis. BMC Infect Dis 6: 67.
  14. Paris L, 2017. Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity. Sci Transl Med 9: eaal2807.
  15. Wolf H, 2008. Diagnosis of pediatric pulmonary tuberculosis by stool PCR. Am J Trop Med Hyg 79: 893898.
  16. Cordova J, 2010. Evaluation of molecular tools for detection and drug susceptibility testing of Mycobacterium tuberculosis in stool specimens from patients with pulmonary tuberculosis. J Clin Microbiol 48: 18201826.
  17. Oberhelman RA, 2010. Diagnostic approaches for paediatric tuberculosis by use of different specimen types, culture methods, and PCR: a prospective case-control study. Lancet Infect Dis 10: 612620.
  18. Nicol MP, Spiers K, Workman L, Isaacs W, Munro J, Black F, Zemanay W, Zar HJ, , 2013. Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children. Clin Infect Dis 57: e18e21.
  19. LaCourse SM, 2018. Stool Xpert MTB/RIF and urine lipoarabinomannan for the diagnosis of tuberculosis in hospitalized HIV-infected children. AIDS 32: 6978.
  20. Ramos E, 2010. Optimizing tuberculosis testing for basic laboratories. Am J Trop Med Hyg 83: 896901.
  21. Friedrich SO, Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics (PanACEA) , 2013. Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment. Lancet. Respir Med 1: 462470.
  22. Datta S, Sherman JM, Bravard M, Valencia T, Gilman RH, Evans CA, , 2015. Clinical evaluation of tuberculosis viability microscopy for assessing treatment response. Clin Infect Dis 60: 11861195.
  23. Hellyer TJ, DesJardin LE, Teixeira L, Perkins MD, Cave MD, Eisenach KD, , 1999. Detection of viable Mycobacterium tuberculosis by reverse transcriptase-strand displacement amplification of mRNA. J Clin Microbiol 37: 518523.
  • Received : 12 Jun 2018
  • Accepted : 14 Jun 2018

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