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- ISSN: 0002-9637
- E-ISSN: 1476-1645
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fn1Authors’ addresses: Mahamoud Sama Cherif, Department of Immunogenetics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan, and Department of Medecine, Universite Gamal Abdel Nasser de Conakry, Commune de Dixinn, Conakry, Guinea, E-mail: msamafr@gmail.com. Shyam Prakash Dumre and Kenji Hirayama, Department of Immunogenetics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan, E-mails: sp.dumre@gmail.com and hiraken@nagasaki-u.ac.jp. Diénaba Kassé, Facely Camara, Alpha Koné, Mandiou Diakité, Mohamed Cissé, and Mamadou Pathé Diallo, Department of Medecine, Universite Gamal Abdel Nasser de Conakry, Conakry, Guinea, E-mails: dienabak@yahoo.fr, facelyfr@yahoo.fr, alafekone@gmail.com, mandioud@yahoo.fr, cissebibi1@gmail.com, and bapathediallo@yahoo.fr. Fatoumata Cherif, Ministry of Health and Public Hygiene, Agence Nationale de Sécurité Sanitaire, Conakry, Guinea, E-mail: fatoumatacherif82@yahoo.fr. Edouard Le Gall, Pôle Régional de Cancérologie Bretagne, Rennes, Rennes, France, and Department of Medecine, Universite Gamal Abdel Nasser de Conakry, Conakry, Guinea, E-mail: edouard.le.gall@chu-rennes.fr. Juntra karbwang, Department of Product Development, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan, E-mail: karbwangj@nagasaki-u.ac.jp.
- The American Society of Tropical Medicine and Hygiene
- Source: The American Journal of Tropical Medicine and Hygiene, Volume 98, Issue 1, Jan 2018, p. 198 - 202
Prognostic and Predictive Factors of Ebola Virus Disease Outcome in Elderly People during the 2014 Outbreak in Guinea
Abstract
Abstract.
Elderly people occupy a prominent position in African societies; however, their potential linkage to high case fatality rate (CFR) in Ebola virus disease (EVD) was often overlooked. We describe the predictive factors for EVD lethality in the elderly. A total of 2,004 adults and 309 elderly patients with confirmed EVD were included in the analysis. The median age (interquartile range) was 35 years (23–44) in adults and 65 years (60–70) in the elderly. The proportion of funeral participation was significantly higher in the elderly group than in the adult group. Duration (in days) between the onset of symptoms and admission was significantly longer in elderly. CFR in the elderly people was also significantly higher (80.6%) than in the adult group (66.2%). Funeral participation constituted a risk factor for the transmission of EVD in elderly people.
© The American Society of Tropical Medicine and Hygiene
- 09 May 2017
- 28 Aug 2017