Blastomycosis and Some Other Conditions Due to Yeast-Like Fungi (Budding Fungi)

Aldo Castellani Department of Tropical Medicine, Tulane University of Louisiana

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The term Blastomycosis sensu lato covers all conditions due to yeast-like fungi but from a practical point of view it is of advantage—as it is usually done in this country—to limit its meaning to denote solely or principally a clinical entity or, more correctly, a group of closely allied entities characterized by the presence of granulomatous, verrucoid lesions in which fungi of the type Blastomycoides are found.

Yeast-like fungi. The term “yeast-like fungi” or “budding fungi” is unscientific, but useful in practice. “Yeast-like fungi” are fungi which in the lesions appear as free oval or roundish cells, some of them budding, with usually no mycelium at all, exceptionally a few mycelial elements. In cultures there may be only budding cells, or budding cells and mycelium or mycelia only. Morphologically, in the lesions two principal types of yeast-like fungi may be distinguished (a) the blastomycetoid (Blastomycetic) type, (b) the cryptococcoid (saccharomycetic) type.

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