On the Chemistry of the Leprosy Organism

Part IV

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  • Tartu (Dorpat)

Summary

The cultivated bacilli of all the authors named in the introduction, and the leprosy bacillus from the lesions, invariably behave identically in microchemical analysis. They were also identical in all comparative staining reactions made before the analysis.

The leprosy bacilli contain: free nucleic acid, bound nucleic acid as nuclear protein principally in their rod-shaped membranes, karyonic acid in the granules, free lipoid chiefly in the membranes but also in the granules, lipoproteins especially in the granules—in which the lipoid-protein combination is bound with a Gram-positive lipoid acid besides the acid components of the lipoprotein that are soluble in alcohol and also one soluble in ether, plasteoprotein in the granules, and a skeleton of basic proteins.

These results add weight, because of the identity of the findings, to the conclusion that these cultures are cultures of the bacillus of leprosy.

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