Treatment of T. Saginata and H. Nana Infestations with Atabrine

Mark T. Hoekenga
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Summary

  1. 1. Atabrine hydrochloride, administered in a dose of 0.8 Gm, orally to 35 patients with T. saginata, caused the passage of a tapeworm in 32 instances. In 24 of the 35 (68.5 per cent) the scolex was found.
  2. 2. Atabrine hydrochloride administered in the same dose orally to 5 children with H. nana was not particularly effective, causing only temporary disappearance of ova from the stools.
  3. 3. There were no serious toxic reactions to the use of atabrine in the dosage described. In 8 cases (20 per cent) there was nausea and vomiting; in 3 instances the vomiting was marked enough to cause failure of the treatment.
  4. 4. Atabrine is, therefore, a valuable teniafuge. It is easily administered, can be repeated more quickly than oleoresin of aspiidium if it is necessary to do so, and it causes only transient toxic reactions.

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