Part II—Investigations of Vertebrate Hosts and Arthropod Vectors

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  • 1 From the Laboratory of the Yellow Fever Research Service, Rio de Janeiro, Brazil

During the years following the first laboratory passage in 1928 of yellow fever virus to monkeys, a mass of information has been accumulated on the susceptibility of vertebrates to infection with the virus and the ability of arthropods to retain or transmit it. A classified list of publications on this subject will be found in the August 1945 issue of the Tropical Diseases Bulletin. In the following review reference will be made only to articles of pertinent interest. We shall, however, refer to some unpublished data.

In interpreting the practical implications of the experimental work on vertebrate hosts and arthropod vectors of the virus, consideration must be given to the methods and criteria adopted in determining the susceptibility of a vertebrate and the ability of an arthropod to transmit the virus. Also the knowledge gained in the laboratory should be weighed in the light of field experience and the ecology of the host and vector involved. The one may serve to complement or to contradict the other.