Chemotherapy of Experimental Histoplasmosis in White Mice

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  • Department of Bacteriology, Medical College of Virginia, Richmond, Virginia

Summary and Conclusions

  1. 1.Intravenous inoculation of white mice with Histoplasma capsulatum is a satisfactory method for the study of the disease in animals, and may be used in studying the chemotherapeutic effect of drugs.
  2. 2.The drugs sodium iodide, neostam, fuadin, sulfanilamide, proflavin, thymol, B-9 and sodium propionate were ineffective in the treatment of histoplasmosis in white mice, according to our criteria.

Author Notes

Fellow in the division of Graduate Study, Medical College of Virginia, School of Dentistry.