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Discussion of the question whether yaws and syphilis are the same or different diseases has been going on for many years. Formerly it ranged over the clinical field, and concerned itself with differences in the morphology of lesions. Since the discovery of the specific germs, the controversy has extended to include the experimental field.
A glance at the literature of the past decade seems to indicate that the discussion is not as brisk now as it once was. The Index Medicus lists under the heading of Frambersia all current medical contributions on yaws and its relation to syphilis. The number of linear column centimeters occupied by the articles on frambesia in the past ten years are as follows: 19, 19, 16, 22 (in 1933), 18, 16, 16, 12, 9, 11. A subject of live interest shows increased bulk in the literature, as witness Sulfanilamide and Derivatives, which climbed from 37 linear centimeters in 1937 to 330 in 1939.