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Disseminated Cutaneous Leishmaniasis Caused by Leishmania major in Immunocompetent Sudanese Child
Abdelsalam Nail
Abdelsalam Nail
Department of Internal Medicine, Faculty of Medicine, Omdurman Islamic University, Tropical Diseases Teaching Hospital, Omdurman, Sudan;
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Elwaleed M. Elamin
Elwaleed M. Elamin
Faculty of Medical Laboratories, Alzaim Alazhary University, Bioscience Research Institute, Khartoum, Sudan;
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Omaima Abdel Majeed Salih
Omaima Abdel Majeed Salih
Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Odurman Islamic University, Tropical Diseases Hospital, Omdurman, Sudan;
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Yousif M. Kordofani
Yousif M. Kordofani
Tropical Diseases Teaching Hospital, Omdurman, Sudan;
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Musa M. Kheir
Musa M. Kheir
Tropical Diseases Teaching Hospital, Omdurman, Sudan;
Bioscience Research Institute, Khartoum, Sudan;
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Bioscience Research Institute, Khartoum, Sudan;
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Maowia M. Mukhtar
mmukhtar@tropmedicine.org
Maowia M. Mukhtar
Bioscience Research Institute, Khartoum, Sudan;
Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan
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Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan
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Leishmania major is the predominant cause of cutaneous leishmaniasis (CL) in Sudan. The disease frequently presents as localized skin lesions that usually heals spontaneously. A 10-year-old girl from Darfur, presented to Khartoum Dermatology Hospital with a 1-year history of widespread skin lesions. The lesions began as small papules on her upper and lower limbs and progressively involved all exposed areas, including her face, over 5 months. Diagnosis was confirmed by parasitology and culture from lesions aspirates. Leishmania major was identified by polymerase chain reaction. The patient was initially treated with intramuscular sodium stibogluconate (10 mg/kg) for 1 month, with no significant improvement. Subsequently, intravenous liposomal amphotericin B (Ambisome) was administered at a dose of 2.5 mg/kg daily in dextrose 5% for 14 days. Marked clinical improvement was observed, with lesions beginning to heal. Treatment was extended for an additional 40 days. The patient showed full recovery, with healed lesions leaving scars.
Author Notes
Disclosures: This case report received approval from the institutional ethics committee. Informed consent was obtained from the patient’s parent to publish clinical data and photographs.
Current contact information: Abdelsalam Nail, Department of Internal Medicine, Faculty of Medicine, Omdurman Islamic University, Tropical Diseases Teaching Hospital, Omdurman, Sudan, E-mail: abdelsalamnail@yahoo.com. Elwaleed M. Elamin, Faculty of Medical Laboratories, Alzaim Alazhary University, Bioscience Research Institute, Khartoum, Sudan, E-mail: wmelamin@hotmail.com. Omaima Abdel Majeed Salih, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Odurman Islamic University, Tropical Diseases Hospital, Omdurman, Sudan, E-mail: omaimanail@yahoo.com. Yousif M. Kordofani, Tropical Diseases Teaching Hospital, Omdurman, Sudan, E-mail: y.m.kordofani@gmail.com. Musa M. Kheir, Department of Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan, E-mail: kheirmusa@hotmail.com. Maowia M. Mukhtar, Bioscience Research Institute, Khartoum, Sudan, E-mail: mmukhtar@bioscience-sd.org.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 836 | 836 | 836 |
| Full Text Views | 23 | 23 | 23 |
| PDF Downloads | 9 | 9 | 9 |