Article Category:
Case Report

A Rare Case of Isolated Pulmonary Leishmaniasis

Nicolas Degand Laboratoire de Biologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France;

Search for other papers by Nicolas Degand in
Current site
Google Scholar
PubMed Close
,
Louis Dan Medioni Laboratoire d’Anatomie Pathologique Medipath, Mougins, France;

Search for other papers by Louis Dan Medioni in
Current site
Google Scholar
PubMed Close
,
Bethan Eveleigh Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France;

Search for other papers by Bethan Eveleigh in
Current site
Google Scholar
PubMed Close
,
Johanna Laurent Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France;

Search for other papers by Johanna Laurent in
Current site
Google Scholar
PubMed Close
,
Tomy Anfrie Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France;

Search for other papers by Tomy Anfrie in
Current site
Google Scholar
PubMed Close
,
Nouhaila Fadil Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France;

Search for other papers by Nouhaila Fadil in
Current site
Google Scholar
PubMed Close
,
Sidali Benyoussef Service de Pneumologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France;

Search for other papers by Sidali Benyoussef in
Current site
Google Scholar
PubMed Close
,
Olivier Raguin Service de Pneumologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France;

Search for other papers by Olivier Raguin in
Current site
Google Scholar
PubMed Close
,
Josephine Dorin Laboratoire de Biologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France;

Search for other papers by Josephine Dorin in
Current site
Google Scholar
PubMed Close
,
Veronique Blanc Laboratoire de Biologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France;

Search for other papers by Veronique Blanc in
Current site
Google Scholar
PubMed Close
,
Christophe Ravel CNR des Leishmanies, Montpellier, France;

Search for other papers by Christophe Ravel in
Current site
Google Scholar
PubMed Close
, and
Christelle Pomares Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France;
Inserm U1065, Mediterranean Center for Molecular Medicine (C3M), Côte d’Azur University, Nice, France

Search for other papers by Christelle Pomares in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.24-0757
Volume/Issue:
Ahead of Print
Restricted access
Get Permissions

Leishmaniasis caused by Leishmania infantum is endemic in the south of France. Here, we report a case of isolated pulmonary leishmaniasis in a patient with chronic obstructive pulmonary disease. In November 2023, the patient underwent a transbronchial biopsy, which resulted in a histopathological diagnosis of leishmaniasis. This finding was confirmed by polymerase chain reaction (PCR) testing targeting Leishmania species on the biopsy tissue and positive serology, although the results of PCR testing on peripheral blood were negative. These results supported a diagnosis of isolated pulmonary leishmaniasis. Additionally, no clinical or biological indicators of visceral leishmaniasis were identified. Atypical forms of leishmaniasis are rare and often lead to delayed diagnosis. In cases with unusual clinical presentations and a history of exposure in an endemic area, evaluation for leishmaniasis should include a comprehensive assessment of all potentially affected organs, regardless of the patient’s immune status.

Author Notes

Current contact information: Nicolas Degand, Josephine Dorin, and Veronique Blanc, Laboratoire de Biologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France, E-mails: nicolas.degand@ch-antibes.fr, josephine.dorin@ch-antibes.fr, and veronique.blanc@ch-antibes.fr. Louis Dan Medioni, Laboratoire d’Anatomie Pathologique Medipath, Mougins, France, E-mail: d.medioni@medipath.fr. Bethan Eveleigh, Johanna Laurent, Tomy Anfrie, Nouhaila Fadil, and Christelle Pomares, Parasitology Mycology Laboratory of the Teaching Hospital of Nice, Nice, France, E-mails: bethan.eveleigh@orange.fr, johanna.laurent@outlook.com, tomylebo@hotmail.fr, nouhailafadil97@gmail.com, and pomares.c@chu-nice.fr. Sidali Benyoussef and Olivier Raguin, Service de Pneumologie, Centre Hospitalier d’Antibes-Juan les Pins, Antibes, France, E-mails: sidali.benyoussef@ch-antibes.fr and olivier.raguin@ch-antibes.fr. Christophe Ravel, CNR des Leishmanies, Montpellier, France, E-mail: christophe.ravel@umontpellier.fr.

Address correspondence to Christelle Pomares, Hôpital de l’Archet, 151 Route de Saint Antoine de Ginestière, CS 23079 06202 Nice 3, France. E-mail: pomares.c@chu-nice.fr
Copyright:
© American Society of Tropical Medicine and Hygiene 2025
Received:
11 Nov 2024
|
Accepted:
27 Jan 2025
|
Published Online:
20 May 2025
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Online ISSN:
1476-1645

Leprosy

By Sir Leonard Rogers and Ernest Muir. Pp. i–xii, 1–260. Second Edition, Williams & Wilkins Co., Baltimore, Md., 1940

Goldberger on Pellagra

ed. by Milton Terris, Professor of Preventive Medicine, New York Medical College. xii + 395 pages. Louisiana State University Press, Baton Rouge, Louisiana. 1964. $12.50

Past two years Past Year Past 30 Days
Abstract Views 764 764 589
Full Text Views 13 13 4
PDF Downloads 22 22 5
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save