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Subcutaneous basidiobolomycosis is a rare chronic granulomatous infection, typically affecting skin and soft tissues of immunocompetent individuals in tropical and subtropical regions. We report a case of an elderly woman presenting with an indurated, progressively enlarging swelling on her distal forearm, initially resembling cellulitis. Despite multiple antibiotic courses and incision procedures, there was no improvement. Biopsy revealed hyperplastic squamous epithelium with granulomas and large aseptate hyphal structures, confirming basidiobolomycosis. The patient was treated with oral itraconazole, leading to significant resolution of the swelling within 3 months. This case highlights the atypical presentation of basidiobolomycosis in an elderly patient and emphasizes the importance of considering this diagnosis in subcutaneous swellings, especially in tropical climates. The case also underscores the challenges in diagnosing this condition, particularly when cultures are negative, and the need for further research to improve diagnostic methods.
Disclosure: The patient provided written-informed consent to the publication of his case details.
Current contact information: Rhea Ahuja, Vanshika Arora, and Neetu Bhari, Department of Dermatology, Venereology, and Leprology, All India Institute of Medical Sciences, New Delhi, India, E-mails: ahujarhea1@gmail.com, vanshika1.arora@gmail.com, and drntbhari@gmail.com. Arshi Tandon and Sudheer Arava, Department of Pathology, All India Institute of Medical Sciences, New Delhi, India, E-mails: arshi.tandon@gmail.com and aravaaiims@gmail.com.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 138 | 138 | 138 |
Full Text Views | 6 | 6 | 6 |
PDF Downloads | 10 | 10 | 10 |