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Patch Test-Positive Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Due to Cycloserine in Multidrug-Resistant Tuberculosis: A Case Report with a Review of the Literature
Priyadharshini Basavarajpura Vijay
Priyadharshini Basavarajpura Vijay
Department of Dermatology, Maulana Azad Medical College, New Delhi, India
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Mrinal Kanti Das
Mrinal Kanti Das
Department of Dermatology, Maulana Azad Medical College, New Delhi, India
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Amar Bahadur
Amar Bahadur
Department of Dermatology, Maulana Azad Medical College, New Delhi, India
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Chirantan Shivaji
Chirantan Shivaji
Department of Dermatology, Maulana Azad Medical College, New Delhi, India
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Tanvi Dev
ivnat2008@gmail.com
Tanvi Dev
Department of Dermatology, Maulana Azad Medical College, New Delhi, India
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Antitubercular treatment (ATT) is associated with multiple cutaneous adverse drug reactions. Second-line ATT is also associated with numerous adverse reactions; however, cutaneous reactions are under-reported. Oral drug provocation (ODP) in multidrug-resistant tuberculosis is challenging because of the paucity of time and the risk of developing secondary drug resistance in the case of interrupted medication. In this paper, we report a case of drug reaction with eosinophilia and systemic symptoms caused by cycloserine in an 18-year-old girl, which was confirmed with ODP and a patch test.
Author Notes
Current contact information: Priyadarshini Basavarajpura Vijay, Mrinal Kanti Das, Amar Bahadur, Chirantan Shivaji, and Tanvi Dev, Maulana Azad Medical College, New Delhi, India, E-mails: priyarakesh95@gmail.com, mrinalkgt@gmail.com, amar921198@gmail.com, chiranthan2013s@gmail.com, and ivnat2008@gmail.com.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 374 | 374 | 374 |
| Full Text Views | 6 | 6 | 6 |
| PDF Downloads | 8 | 8 | 8 |