Case Report: Brucellosis Mimicking Tuberculous Meningitis in a Child

Sevgi Aslan Tuncay Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Gulsen Akkoc Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Seyhan Yilmaz Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Burcu Parlak Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Pinar Canizci Erdemli Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Aylin Dizi Isik Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Eda Kepenekli Marmara University School of Medicine, Department of Pediatric Infectious Diseases, Istanbul, Turkey

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Neurobrucellosis is rare in children, presenting with a variety of clinical manifestations, including meningitis, meningoencephalitis, cranial neuropathies, and intracranial mass-like lesions. We present a case of a 17-year-old girl admitted to the hospital in Istanbul for headache. Lumbar puncture showed elevated intracranial pressure, monocytic pleocytosis, elevated total protein, and hypoglycorrhachia. Brucella melitensis grew from the cerebrospinal fluid. The patient was treated with doxycycline, rifampin, amikacin, and ceftriaxone and showed persistent sensorineural hearing loss. It is essential to consider brucellosis in the differential diagnosis of infectious neurological disease in areas where the disease is endemic. Serologic tests and cultures are needed for diagnosis, and efforts need to be made to identify the infecting organism to the species level to guide zoonotic source control efforts.

Author Notes

Current contact information: Sevgi Aslan Tuncay, Gülşen Akkoç, Seyhan Yılmaz, Burcu Parlak, Pınar Canizci Erdemli, and Aylin Dizi Işık, Marmara University Faculty of Medicine, Department of Pediatric Infectious Disease, Istanbul, Turkey, E-mails: aslan.svgi@gmail.com, agulsenakkoc@gmail.com, seyhanbirinci@gmail.com, drbparlak47@gmail.com, pinarcanizci@hotmail.com, and aylindizi_91@hotmail.com. Eda Kepenekli, Bahcesehir University, Medical Park Goztepe Hospital, Department of Pediatric Infectious Diseases, Istanbul, Turkey, E-mail: ekepenekli@yahoo.com.

Address correspondence to Eda Kepenekli, Fevzi Çakmak, Muhsin Yazıcıoğlu St. No: 10, Floor: 6, Department of Pediatrics, Pendik/Istanbul, Turkey. E-mail: ekepenekli@yahoo.com
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