Case Report: Splenic Infarction in Infectious Mononucleosis due to Epstein–Barr Virus Infection

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  • 1 Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan

Epstein–Barr virus (EBV) is the most common cause of infectious mononucleosis (IM) and IM is a clinical syndrome typically characterized by fever, pharyngitis, and cervical lymph node enlargement. We describe the case of a 19-year-old man with IM complicated by splenic infarction. The patient visited our hospital because of upper abdominal pain without a fever and sore throat. Abdominal computed tomography revealed a low-density area in the spleen, which indicated splenic infarction. The next day, he developed a fever. After diminishing abdominal pain and fever, he developed pharyngitis accompanied by fever. Acute EBV infection was confirmed by serological tests. The patient was successfully managed with no specific therapy. Splenic infarction is a rare complication of IM and this case showed that splenic infarction can precede a fever and pharyngitis.

Author Notes

Address correspondence to Hiroaki Nishioka, Department of General Internal Medicine, Kobe City Medical Center General Hospital, 2-1-1 Minami-machi, Minatojima, Chuo-ku, Kobe, Hyogo 650-0047, Japan. E-mail: nishiokahiroaki@hotmail.com

Authors’ addresses: Hiroaki Nishioka, Katsuma Hayashi, and Hayato Shimizu, Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Kyogo, Japan, E-mails: nishiokahiroaki@hotmail.com, katsuma5miffy@gmail.com, and hash_mother_lake1008@yahoo.co.jp.

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