Case Report: A Human Case of Onchocerca lupi Mimicking Nodular Scleritis

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  • 1 Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey;
  • | 2 Byers Eye Institute, Stanford University, Palo Alto, California;
  • | 3 Ocular Imaging Research and Reading Center, Sunnyvale, California;
  • | 4 Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy;
  • | 5 Department of Pathology, School of Medicine, Gazi University, Ankara, Turkey;
  • | 6 Department of Microbiology, School of Medicine, Gazi University, Ankara, Turkey;
  • | 7 Department of Pathobiology, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, Iran

We report a case of human ocular onchocerciasis by zoonotic Onchocerca lupi presenting as nodular scleritis. Molecular analyses were used to confirm diagnosis at species level. In addition to few existing reports of human infection by O. lupi in Turkey, this case further suggests that the pathogen might be more common than previously reported, thus requiring further attention and investigations.

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Author Notes

Address correspondence to Murat Hasanreisoglu, Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey. E-mail: rmurat95@yahoo.com

Authors’ addresses: Murat Hasanreisoglu, Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey, and Byers Eye Institute, Stanford University, Palo Alto, CA, E-mail: rmurat95@yahoo.com. Muhammad Sohail Halim, Byers Eye Institute, Stanford University, Palo Alto, CA, and Ocular Imaging Research and Reading Center, Sunnyvale, CA, E-mail: sohailhaleem@gmail.com. Maria Stefania Latrofa and Jairo Alfonso Mendoza-Roldan, Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy, E-mails: maria.latrofa@uniba.it and jairo.mendozaroldan@uniba.it. Betül Öğüt and İpek Işık Gönül, Department of Pathology, School of Medicine, Gazi University, Ankara, Turkey, E-mails: betulcimer@gmail.com and dripek@gmail.com. Mervenur Yılmaz and Atike Burçin Tefon Aribas, Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey, E-mails: mrvnr13@gmail.com and burcintefon@gmail.com. Kayhan Caglar and Funda Dogruman-Al, Department of Microbiology, School of Medicine, Gazi University, Ankara, Turkey, E-mails: kcaglar@gazi.edu.tr and alfunda@gazi.edu.tr. Quan Dong Nguyen, Byers Eye Institute, Stanford University, Palo Alto, CA, E-mail: ndquan@stanford.edu. Domenico Otranto, Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy, and Department of Pathobiology, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, Iran, E-mail: domenico.otranto@uniba.it.

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