Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Wiwanitkit V, 2010. Non vector-borne transmission modes of dengue. J Infect Dev Ctries 4: 51–54.
-
2.
Wilder-Smith A, Chen LH, Massad E, Wilson ME, 2009. Threat of dengue to blood safety in dengue-endemic countries. Emerg Infect Dis 15: 8.
-
3.
Faddy HM, Seed CR, Fryk JJ, Hyland CA, Ritchie SA, Taylor CT, Van Der Merwe KL, Flower RL, McBride WJ, 2013. Implications of dengue outbreaks for blood supply, Australia. Emerg Infect Dis 19: 787.
-
4.
Chen LH, Wilson ME, 2004. Transmission of dengue virus without a mosquito vector: nosocomial mucocutaneous transmission and other routes of transmission. Clin Infect Dis 39: e56–e60.
-
5.
Basurko C, Carles G, Youssef M, Guindi WE, 2009. Maternal and fetal consequences of dengue fever during pregnancy. Eur J Obstet Gynecol Reprod Biol 147: 29–32.
-
6.
Guzman MG et al.., 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8: S7–S16.
-
7.
Bhatt S et al.., 2013. The global distribution and burden of dengue. Nature 496: 504–507.
-
8.
Burke DS, Nisalak A, Johnson DE, Scott RM, 1988. A prospective study of dengue infections in Bangkok. Am J Trop Med Hyg 38: 172–180.
-
9.
Pouliot SH, Xiong X, Harville E, Paz-Soldan V, Tomashek KM, Breart G, Buekens P, 2010. Maternal dengue and pregnancy outcomes: a systematic review. Obstet Gynecol Surv 65: 107–118.
-
10.
Lanciotti RS, Calisher CH, Gubler DJ, Chang G-J, Vorndam AV, 1992. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30: 545–551.
-
11.
Dussart P et al.., 2006. Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum. Clin Vaccine Immunol 13: 1185–1189.
-
12.
Talarmin A, Labeau B, Lelarge J, Sarthou J-L, 1998. Immunoglobulin A-specific capture enzyme-linked immunosorbent assay for diagnosis of dengue fever. J Clin Microbiol 36: 1189–1192.
-
13.
World Health Organization and the Special Programme for Research and Training in Tropical Diseases (TDR), 2009. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control: New Edition. Geneva, Switzerland: World Health Organization.
-
14.
Peeling RW et al.., 2010. Evaluation of diagnostic tests: dengue. Nat Rev Microbiol 8: S30–S37.
-
15.
Argolo AF, Féres VC, Silveira LA, Oliveira AC, Pereira LA, Júnior JBS, Braga C, Martelli CM, 2013. Prevalence and incidence of dengue virus and antibody placental transfer during late pregnancy in central Brazil. BMC Infect Dis 13: 254.
-
16.
Sirinavin S, Nuntnarumit P, Supapannachart S, Boonkasidecha S, Techasaensiri C, Yoksarn S, 2004. Vertical dengue infection: case reports and review. Pediatr Infect Dis J 23: 1042–1047.
-
17.
Janjindamai W, Pruekprasert P, 2003. Perinatal dengue infection: a case report and review of literature. Southeast Asian J Trop Med Public Health 34: 793–796.
-
18.
Boussemart T, Babe P, Sibille G, Neyret C, Berchel C, 2001. Prenatal transmission of dengue: two new cases. J Perinatol 21: 255–257.
-
19.
Chotigeat U, Kalayanarooj S, Nisalak A, 2003. Vertical transmission of dengue infection in Thai infants: two case reports. J Med Assoc Thai 86: S628–S632.
-
20.
Fatimil LE, Mollah AH, Ahmed S, Rahman M, 2003. Vertical transmission of dengue: first case report from Bangladesh. Southeast Asian J Trop Med Public Health 34: 800–803.
-
21.
Tan PC, Rajasingam G, Devi S, Omar SZ, 2008. Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome. Obstet Gynecol 111: 1111–1117.
-
22.
Tsai H-C, Lin C-C, Hong N-S, Kuo T-N, Huang Y-Y, Lin MY-S, Loo TC, Huang KF, Wang JJ, Chen SH, 2010. Dengue virus infection in early gestation with delivery of an unaffected fetus and no vertical transmission. Taiwan J Obstet Gynecol 49: 112–114.
-
23.
Tan PC, Soe MZ, Si Lay K, Wang SM, Sekaran SD, Omar SZ, 2012. Dengue infection and miscarriage: a prospective case control study. PLoS Negl Trop Dis 6: e1637.
-
24.
Chye JK, Lim CT, Ng KB, Lim JM, George R, Lam SK, 1997. Vertical transmission of dengue. Clin Infect Dis 25: 1374–1377.
-
25.
Thaithumyanon P, Thisyakorn U, Deerojnawong J, Innis BL, 1994. Dengue infection complicated by severe hemorrhage and vertical transmission in a parturient woman. Clin Infect Dis 18: 248–249.
-
26.
Carroll ID, Toovey S, Van Gompel A, 2007. Dengue fever and pregnancy—a review and comment. Travel Med Infect Dis 5: 183–188.
-
27.
Barthel A, Gourinat A-C, Cazorla C, Joubert C, Dupont-Rouzeyrol M, Descloux E, 2013. Breast milk as a possible route of vertical transmission of dengue virus? Clin Infect Dis 57: 415–417.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2048 | 1351 | 47 |
| Full Text Views | 1139 | 24 | 2 |
| PDF Downloads | 561 | 27 | 4 |
Estimating the Risk of Vertical Transmission of Dengue: A Prospective Study
Célia Basurko
Célia Basurko
Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
Equipe EA3593, Ecosystèmes amazoniens et Pathologie Tropicale, Université de la Guyane, Cayenne, French Guiana, France;
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Equipe EA3593, Ecosystèmes amazoniens et Pathologie Tropicale, Université de la Guyane, Cayenne, French Guiana, France;
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Séverine Matheus
Séverine Matheus
Laboratoire de virologie, Centre National de Référence des Arbovirus, Institut Pasteur de la Guyane Cayenne, French Guiana, France;
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Hélène Hildéral
Hélène Hildéral
Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
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Sibille Everhard
Sibille Everhard
Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
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Marion Restrepo
Marion Restrepo
Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
Pôle de santé publique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
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Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
Pôle de santé publique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
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Emma Cuadro-Alvarez
Emma Cuadro-Alvarez
Service de pédiatrie, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
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Véronique Lambert
Véronique Lambert
Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
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Rachida Boukhari
Rachida Boukhari
Service d’analyses médicales, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
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Jean-Pierre Duvernois
Jean-Pierre Duvernois
Service de gynécologie et d’obstétrique, Centre médico-chirurgical de Kourou, Croix Rouge Française, Kourou, French Guiana, France;
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Anne Favre
Anne Favre
Réseau périnat de Guyane, Cayenne, French Guiana, France
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Mathieu Nacher
Mathieu Nacher
Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France;
Equipe EA3593, Ecosystèmes amazoniens et Pathologie Tropicale, Université de la Guyane, Cayenne, French Guiana, France;
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Equipe EA3593, Ecosystèmes amazoniens et Pathologie Tropicale, Université de la Guyane, Cayenne, French Guiana, France;
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Gabriel Carles
Gabriel Carles
Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France;
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The incidence of dengue worldwide is increasing rapidly. A better understanding of dengue transmission may help improve interventions against this major public health problem. The virus is mostly transmitted by vectors. There are, however, other modes of transmission, notably mother-to-child transmission or vertical transmission. We studied a prospective cohort of 54 women who had dengue while pregnant during the 2012–2013 epidemic in French Guiana to estimate the mother-to-child transmission rate and assess the clinical and biological presentation of neonatal dengue. The rate of vertical transmission was between 18.5% (95% confidence interval [CI]: 9.25–31.4) and 22.7% (95% CI: 11.5–37.8), depending on the calculation method used. Mother-to-child transmission occurred both in early and late pregnancy. There were 52 births, including three newborns who presented neonatal dengue with warning signs requiring platelet transfusion. This quantification of the mother-to-child transmission of dengue highlights three points: first, vertical transmission of dengue is not negligible; second, it is more frequent when maternal dengue occurs late during pregnancy near delivery; and third, reliable diagnostic tests must be used to allow the diagnosis of vertical transmission. Our findings indicate that if there is a known history of maternal dengue during pregnancy, or if there is fever during the 15 days before term, cord blood and placenta should be sampled after delivery and tested for the virus, and the newborn should be closely monitored during the postpartum period.
Author Notes
Financial support: This study was funded by European public funds (PO-FEDER 2007-2013 program; presage number 31257), by the Pasteur Institute, and by Cayenne General Hospital.
Authors’ addresses: Célia Basurko and Mathieu Nacher, Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France and Equipe EA3593, Ecosystèmes amazoniens et Pathologie Tropicale, Université de la Guyane, Cayenne, French Guiana, France, E-mails: cbasurko@gmail.com and mathieu.nacher@ch-cayenne.fr. Séverine Matheus, Laboratoire de virologie, Centre National de Référence des Arbovirus, Institut Pasteur de la Guyane Cayenne, French Guiana, France, E-mail: smatheus@pasteur-cayenne.fr. Hélène Hildéral and Sibille Everhard, Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France, E-mails: helene.hilderal@ch-cayenne.fr and sibille.everhard@gmail.com. Marion Restrepo, Centre d’Investigation Clinique Antilles Guyane, Inserm CIC1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France, Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France, and Pôle de santé publique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France, E-mail: marionrestrepo85@gmail.com. Emma Cuadro-Alvarez, Service de pédiatrie, Centre Hospitalier de Cayenne, Cayenne, French Guiana, France, E-mail: emma.cuadro@ch-cayenne.fr. Véronique Lambert and Gabriel Carles, Service de gynécologie et d’obstétrique, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France, E-mails: vlambert2@orange.fr and gabriel.carles@wanadoo.fr. Rachida Boukhari, Service d’analyses médicales, Centre Hospitalier de l’Ouest Guyanais, Saint Laurent du Maroni, French Guiana, France, E-mail: r.boukhari@ch-ouestguyane.fr. Jean-Pierre Duvernois, Service de gynécologie et d’obstétrique, Centre médico-chirurgical de Kourou, Croix Rouge Française, Kourou, French Guiana, France, E-mail: sjpduvernois@orange.fr. Anne Favre, Réseau périnat de Guyane, Cayenne, French Guiana, France, E-mail: anne.favre@ch-cayenne.fr.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Wiwanitkit V, 2010. Non vector-borne transmission modes of dengue. J Infect Dev Ctries 4: 51–54.
-
2.
Wilder-Smith A, Chen LH, Massad E, Wilson ME, 2009. Threat of dengue to blood safety in dengue-endemic countries. Emerg Infect Dis 15: 8.
-
3.
Faddy HM, Seed CR, Fryk JJ, Hyland CA, Ritchie SA, Taylor CT, Van Der Merwe KL, Flower RL, McBride WJ, 2013. Implications of dengue outbreaks for blood supply, Australia. Emerg Infect Dis 19: 787.
-
4.
Chen LH, Wilson ME, 2004. Transmission of dengue virus without a mosquito vector: nosocomial mucocutaneous transmission and other routes of transmission. Clin Infect Dis 39: e56–e60.
-
5.
Basurko C, Carles G, Youssef M, Guindi WE, 2009. Maternal and fetal consequences of dengue fever during pregnancy. Eur J Obstet Gynecol Reprod Biol 147: 29–32.
-
6.
Guzman MG et al.., 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8: S7–S16.
-
7.
Bhatt S et al.., 2013. The global distribution and burden of dengue. Nature 496: 504–507.
-
8.
Burke DS, Nisalak A, Johnson DE, Scott RM, 1988. A prospective study of dengue infections in Bangkok. Am J Trop Med Hyg 38: 172–180.
-
9.
Pouliot SH, Xiong X, Harville E, Paz-Soldan V, Tomashek KM, Breart G, Buekens P, 2010. Maternal dengue and pregnancy outcomes: a systematic review. Obstet Gynecol Surv 65: 107–118.
-
10.
Lanciotti RS, Calisher CH, Gubler DJ, Chang G-J, Vorndam AV, 1992. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30: 545–551.
-
11.
Dussart P et al.., 2006. Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum. Clin Vaccine Immunol 13: 1185–1189.
-
12.
Talarmin A, Labeau B, Lelarge J, Sarthou J-L, 1998. Immunoglobulin A-specific capture enzyme-linked immunosorbent assay for diagnosis of dengue fever. J Clin Microbiol 36: 1189–1192.
-
13.
World Health Organization and the Special Programme for Research and Training in Tropical Diseases (TDR), 2009. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control: New Edition. Geneva, Switzerland: World Health Organization.
-
14.
Peeling RW et al.., 2010. Evaluation of diagnostic tests: dengue. Nat Rev Microbiol 8: S30–S37.
-
15.
Argolo AF, Féres VC, Silveira LA, Oliveira AC, Pereira LA, Júnior JBS, Braga C, Martelli CM, 2013. Prevalence and incidence of dengue virus and antibody placental transfer during late pregnancy in central Brazil. BMC Infect Dis 13: 254.
-
16.
Sirinavin S, Nuntnarumit P, Supapannachart S, Boonkasidecha S, Techasaensiri C, Yoksarn S, 2004. Vertical dengue infection: case reports and review. Pediatr Infect Dis J 23: 1042–1047.
-
17.
Janjindamai W, Pruekprasert P, 2003. Perinatal dengue infection: a case report and review of literature. Southeast Asian J Trop Med Public Health 34: 793–796.
-
18.
Boussemart T, Babe P, Sibille G, Neyret C, Berchel C, 2001. Prenatal transmission of dengue: two new cases. J Perinatol 21: 255–257.
-
19.
Chotigeat U, Kalayanarooj S, Nisalak A, 2003. Vertical transmission of dengue infection in Thai infants: two case reports. J Med Assoc Thai 86: S628–S632.
-
20.
Fatimil LE, Mollah AH, Ahmed S, Rahman M, 2003. Vertical transmission of dengue: first case report from Bangladesh. Southeast Asian J Trop Med Public Health 34: 800–803.
-
21.
Tan PC, Rajasingam G, Devi S, Omar SZ, 2008. Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome. Obstet Gynecol 111: 1111–1117.
-
22.
Tsai H-C, Lin C-C, Hong N-S, Kuo T-N, Huang Y-Y, Lin MY-S, Loo TC, Huang KF, Wang JJ, Chen SH, 2010. Dengue virus infection in early gestation with delivery of an unaffected fetus and no vertical transmission. Taiwan J Obstet Gynecol 49: 112–114.
-
23.
Tan PC, Soe MZ, Si Lay K, Wang SM, Sekaran SD, Omar SZ, 2012. Dengue infection and miscarriage: a prospective case control study. PLoS Negl Trop Dis 6: e1637.
-
24.
Chye JK, Lim CT, Ng KB, Lim JM, George R, Lam SK, 1997. Vertical transmission of dengue. Clin Infect Dis 25: 1374–1377.
-
25.
Thaithumyanon P, Thisyakorn U, Deerojnawong J, Innis BL, 1994. Dengue infection complicated by severe hemorrhage and vertical transmission in a parturient woman. Clin Infect Dis 18: 248–249.
-
26.
Carroll ID, Toovey S, Van Gompel A, 2007. Dengue fever and pregnancy—a review and comment. Travel Med Infect Dis 5: 183–188.
-
27.
Barthel A, Gourinat A-C, Cazorla C, Joubert C, Dupont-Rouzeyrol M, Descloux E, 2013. Breast milk as a possible route of vertical transmission of dengue virus? Clin Infect Dis 57: 415–417.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2048 | 1351 | 47 |
| Full Text Views | 1139 | 24 | 2 |
| PDF Downloads | 561 | 27 | 4 |