Competence of Phortica variegata from the United States as an Intermediate Host of the Thelazia callipaeda Eyeworm

Domenico Otranto Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Italy;

Search for other papers by Domenico Otranto in
Current site
Google Scholar
PubMed
Close
,
Roberta Iatta Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Italy;

Search for other papers by Roberta Iatta in
Current site
Google Scholar
PubMed
Close
,
Riccardo Paolo Lia Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Italy;

Search for other papers by Riccardo Paolo Lia in
Current site
Google Scholar
PubMed
Close
,
Maria Alfonsa Cavalera Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Italy;

Search for other papers by Maria Alfonsa Cavalera in
Current site
Google Scholar
PubMed
Close
,
Jan Màca Czech Entomological Society, Praha, Czech Republic;

Search for other papers by Jan Màca in
Current site
Google Scholar
PubMed
Close
,
Marco Pombi Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma “Sapienza,” Rome, Italy;

Search for other papers by Marco Pombi in
Current site
Google Scholar
PubMed
Close
,
Filipe Dantas-Torres Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Italy;
Aggeu Magalhães Institute, Oswaldo Cruz Foundation Recife, Pernambuco, Brazil;

Search for other papers by Filipe Dantas-Torres in
Current site
Google Scholar
PubMed
Close
, and
John Jaenike University of Rochester, Rochester, New York

Search for other papers by John Jaenike in
Current site
Google Scholar
PubMed
Close
Restricted access

Over the past 20 years, Thelazia callipaeda (the oriental eyeworm) has become endemic in Europe, infecting domestic and wild carnivores and humans. The vector of this nematode, the fruit fly Phortica variegata, has recently been discovered in the United States, and its vector competence is demonstrated for T. callipaeda in this article, therefore representing a potential new threat for infection of carnivores and humans in the United States.

Author Notes

Address correspondence to Domenico Otranto, Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Strada Provinciale per Casamassima km 3, 70010 Valenzano, Bari 70010, Italy. E-mail: domenico.otranto@uniba.it

Authors’ addresses: Domenico Otranto, Roberta Iatta, Riccardo Paolo Lia, and Maria Alfonsa Cavalera, Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Bari, Italy, E-mails: domenico.otranto@uniba.it, roberta.iatta@uniba.it, riccardopaolo.lia@uniba.it, and alfonsacavalera596@gmail.com. Jan Màca, Czech Entomological Society, Praha, Czech Republic, E-mail: janxmaca@seznam.cz. Marco Pombi, Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma “Sapienza,” Rome, Italy, E-mail: marco.pombi@uniroma1.it. Filipe Dantas-Torres, Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Bari, Italy, and Department of Immunology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Pernambuco, Brazil, E-mail: filipe.dantas@cpqam.fiocruz.br. John Jaenike, University of Rochester, Rochester, NY, E-mail: joja@UR.Rochester.edu.

  • 1.

    Otranto D, Dantas-Torres F, Brianti E, Traversa D, Petricì D, Genchi C, Capelli G, 2013. Vector-borne helminths of dogs and humans in Europe. Parasit Vectors 6: 16.

  • 2.

    Otranto D, Dantas-Torres F, Mallia E, DiGeronimo PM, Brianti E, Testini G, Traversa D, Lia RP, 2009. Thelazia callipaeda (Spirurida, Thelaziidae) in wild animals: report of new host species and ecological implications. Vet Parasitol 166: 262267.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3.

    Otranto D, Ferroglio E, Lia RP, Traversa D, Rossi L, 2003. Current status and epidemiological observations of Thelazia callipaeda (Spirurida, Thelaziidae) in dogs, cats and foxes in Italy: a “coincidence” or a parasitic disease of the Old Continent? Vet Parasitol 116: 315325.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    Miró G, Montoya A, Hernández L, Dado D, Vázquez MV, Benito M, Villagrasa M, Brianti E, Otranto D, 2011. Thelazia callipaeda: infection in dogs: a new parasite for Spain. Parasit Vectors 4: 148.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Colella V, Kirkova Z, Fok É, Mihalca AD, Tasić-Otašević S, Hodžić A, Dantas-Torres F, Otranto D, 2016. Increase in eyeworm infections in eastern Europe. Emerg Infect Dis 22: 15131515.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    Otranto D, Brianti E, Cantacessi C, Lia RP, Máca J, 2006. The zoophilic fruit fly Phortica variegata: morphology, ecology and biological niche. Med Vet Entomol 20: 358364.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    Otranto D, Lia RP, Cantacessi C, Testini G, Troccoli A, Shen JL, Wang ZX, 2005. Nematode biology and larval development of Thelazia callipaeda (Spirurida, Thelaziidae) in the drosophilid intermediate host in Europe and China. Parasitology 131: 847855.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Otranto D, Cantacessi C, Testini G, Lia RP, 2006. Phortica variegata as an intermediate host of Thelazia callipaeda under natural conditions: evidence for pathogen transmission by a male arthropod vector. Int J Parasitol 36: 11671173.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    Máca J, Otranto D, 2014. Drosophilidae feeding on animals and the inherent mystery of their parasitism. Parasit Vectors 7: 516.

  • 10.

    Doezie AM, Kucius RW, Aldeen W, Hale D, Sith DR, Mamalis N, 1996. Thelazia californiensis conjuntival infestation. Ophthalmic Surg Lasers 27: 716719.

  • 11.

    Burnett HS, Wagner ED, 1958. Two new definitive hosts for the eye worm, Thelazia californiensis Price, 1930. J Parasitol 44: 502.

  • 12.

    Werner T, Jaenike J, 2017. Drosophilids of the Midwest and Northeast, 2017. New York, NY: River Campus Libraries. Available at: http://humanities.lib.rochester.edu/drosophilaguide/.

    • PubMed
    • Export Citation
  • 13.

    Bächli G, Vilela CR, Escher SA, Saura A, 2005. The Drosophilidae (Diptera) of Fennoscandia and Denmark. Fauna Entomologica Scandinavica, Vol. 39. Leiden, The Netherlands: Brill, 362 pp.

    • PubMed
    • Export Citation
  • 14.

    Otranto D, Testini G, De Luca F, Hu M, Shamsi S, Gasser RB, 2005. Analysis of genetic variability within Thelazia callipaeda (Nematoda: Thelazioidea) from Europe and Asia by sequencing and mutation scanning of the mitochondrial cytochrome c oxidase subunit 1 gene. Mol Cell Probes 19: 306313.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    Otranto D, Stevens JR, Testini G, Cantacessi C, Máca J, 2008. Molecular characterization and phylogenesis of Steganinae (Diptera, Drosophilidae) inferred by the mitochondrial cytochrome c oxidase subunit 1. Med Vet Entomol 22: 3747.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    New York State Department of Environmental Conservation, 2010. Checklist of Amphibians, Reptiles, Birds and Mammals of New York State. Albany, NY: Wildlife Diversity Group.

    • PubMed
    • Export Citation
  • 17.

    Hodžić A, Latrofa MS, Annoscia G, Alić A, Beck R, Lia RP, Dantas-Torres F, Otranto D, 2014. The spread of zoonotic Thelazia callipaeda in the Balkan area. Parasit Vectors 7: 352.

  • 18.

    Mihalca AD, Ionică AM, D’Amico G, Daskalaki AA, Deak G, Matei IA, Şimonca V, Iordache D, Modrý D, Gherman CM, 2016. Thelazia callipaeda in wild carnivores from Romania: new host and geographical records. Parasit Vectors 9: 350.

    • PubMed
    • Search Google Scholar
    • Export Citation
Past two years Past Year Past 30 Days
Abstract Views 99 99 17
Full Text Views 1015 32 4
PDF Downloads 165 20 1
 
Membership Banner
 
 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save