High Prevalence of Shigella or Enteroinvasive Escherichia coli Carriage among Residents of an Internally Displaced Persons Camp in South Sudan

Jesse Bliss Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah;

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Malika Bouhenia World Health Organization, Juba, South Sudan;

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Peter Hale Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah;

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Brianne A. Couturier ARUP Laboratories, Salt Lake City, Utah;

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Anita S. Iyer Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah;

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John Rumunu Republic of South Sudan Ministry of Health, Juba, South Sudan;

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Stephen Martin World Health Organization, Geneva, Switzerland;

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Joseph F. Wamala World Health Organization, Juba, South Sudan;

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Abdinasir Abubakar World Health Organization, Juba, South Sudan;

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David A. Sack Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;

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Francisco J. Luquero Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;
Epicentre, Paris, France;

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Marc Roger Couturier ARUP Laboratories, Salt Lake City, Utah;
Department of Pathology, University of Utah, Salt Lake City, Utah;

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Andrew S. Azman Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;
Médecins sans Frontières, Geneva, Switzerland

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Daniel T. Leung Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah;
Department of Pathology, University of Utah, Salt Lake City, Utah;

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Displaced persons living in camps are at an increased risk of diarrheal diseases. Subclinical carriage of pathogens may contribute to the spread of disease, especially for microbes that require a low infectious dose. Multiplex real-time polymerase chain reaction was performed to detect a panel of 20 bacterial, viral, and protozoal targets, and we report a high prevalence of enteropathogen carriage, including Shigella spp. or enteroinvasive Escherichia coli in 14%, among a sample of 88 asymptomatic individuals in an internally displaced persons camp in South Sudan. Further studies are needed to determine the contribution of such carriage to the spread of disease.

Author Notes

Address correspondence to Daniel T. Leung, Division of Infectious Diseases, University of Utah School of Medicine, 30 North 1900 East, Room 4B319, Salt Lake City, UT 84132. E-mail: daniel.leung@utah.edu

Authors’ addresses: Jesse Bliss, Peter Hale, and Daniel T. Leung, Division of Infectious Diseases, University of Utah, Salt Lake City, UT, E-mails: jesse.bliss@utah.edu, peter.hale@hsc.utah.edu, and daniel.leung@utah.edu. Malika Bouhenia, World Health Organization, Juba, South Sudan, E-mail: malik14@yahoo.fr. Brianne A. Couturier and Marc Roger Couturier, ARUP Laboratories, Salt Lake City, UT, E-mails: brianne.a.couturier@aruplab.com and marc.couturier@aruplab.com. Anita S. Iyer, Division of Infectious Diseases, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, E-mail: anita.iyer@hsc.utah.edu. John Rumunu, Department of Preventative Health, Government of the Republic of South Sudan Ministry of Health, Juba, South Sudan, E-mail: jrumunu@yahoo.com. Stephen Martin, World Health Organization, Geneva, Switzerland, E-mail: martins@who.int. Joseph F. Wamala, World Health Organization, Emergency, Juba, South Sudan, E-mail: wamalaj@who.int. Abdinasir Abubakar, World Health Organization, Juba, South Sudan, E-mail: abubakara@who.int. David A. Sack, Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, E-mail: dsack1@jhu.edu. Francisco J. Luquero, Epicentre, Paris, France, E-mail: francisco.luquero@epicentre.msf.org. Andrew S. Azman, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, and Medecins Sans Frontieres, Geneva, Switzerland, E-mail: azman@jhu.edu.

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