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Case Report: Carbapenemase-Producing Enterobacteriaceae in an Asylum Seeker with Multidrug–Resistant Tuberculosis

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  • 1 University of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, The Netherlands;
  • | 2 Department of Medical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece;
  • | 3 Department of Medical Microbiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands;
  • | 4 Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece;
  • | 5 Department of Pulmonary Diseases and Tuberculosis, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;
  • | 6 Tuberculosis Center Beatrixoord, University of Groningen, University Medical Center Groningen, Haren, The Netherlands
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A Syrian asylum seeker with multidrug–resistant tuberculosis (TB) developed a bronchopleural fistula after pneumonectomy. Although screening tests were negative on admission, carbapenemase-producing Enterobacteriaceae were cultured after a few months of TB treatment. Prevalence of multidrug–resistant organisms is reported to be increased in asylum seekers compared with the general Dutch population. Arduous conditions during transit and interrupted health care delivery in our patient led to multiple-resistant microorganisms that complicated treatment.

Author Notes

Address correspondence to Sofanne J. Ravensbergen, Department of Internal Medicine/Infectious Diseases, University Medical Centre Groningen, P. O. Box 30 001, 9700 RB Groningen, The Netherlands. E-mail: s.j.ravensbergen@umcg.nl

Authors’ addresses: Sofanne J. Ravensbergen, Department of Internal Medicine/Infectious Diseases, University Center of Groningen, Groningen, The Netherlands, E-mail: s.j.ravensbergen@umcg.nl. Christina Louka, Department of Medical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece, E-mail: cslouka@gmail.com. Mariëtte Lokate and Erik Bathoorn, Department of Medical Microbiology, University Medical Center Groningen, Groningen, The Netherlands, E-mails: m.lokate@umcg.nl and d.bathoorn@umcg.nl. Spyros Pournaras, Department of Microbiology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece, E-mail: spyrpournaras@yahoo.gr. Tjip S. van der Werf and Ymkje Stienstra, Department of Internal Medicine/Infectious Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, E-mails: t.s.van.der.werf@umcg.nl and y.stienstra@umcg.nl. Wiel C. M. de Lange and Onno W. Akkerman, Department of Pulmonary Medicine and Tuberculosis, University Medical Center Groningen, Groningen, The Netherlands, E-mails: w.c.m.de.lange@umcg.nl and o.w.akkerman@umcg.nl.

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