ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Taylor SM et al. 2011. Quantification of the burden and consequences of pregnancy-associated malaria in the Democratic Republic of the Congo. J Infect Dis 204: 1762–1771.
-
2.
Miller LH, Baruch DI, Marsh K, Doumbo OK, 2002. The pathogenic basis of malaria. Nature 415: 673–679.
-
3.
Steketee RW, Nahlen BL, Parise ME, Menendez C, 2001. The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg 64: 28–35.
-
4.
van Geertruyden JP, Thomas F, Erhart A, D’Alessandro U, 2004. The contribution of malaria in pregnancy to perinatal mortality. Am J Trop Med Hyg 71: 35–40.
-
5.
Desai M, ter Kuile FO, Nosten F, McGready R, Asamoa K, Brabin B, Newman RD, 2007. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 7: 93–104.
-
6.
Ayres Pereira M et al. 2016. Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on Syndecan-1. PLoS Pathog 12: e1005831.
-
7.
Salanti A et al. 2004. Evidence for the involvement of VAR2CSA in pregnancy-associated malaria. J Exp Med 200: 1197–1203.
-
8.
Beeson JG, Amin N, Kanjala M, Rogerson SJ, 2002. Selective accumulation of mature asexual stages of Plasmodium falciparum-infected erythrocytes in the placenta. Infect Immun 70: 5412–5415.
-
9.
Douki JB, Sterkers Y, Lepolard C, Traore B, Costa FT, Scherf A, Gysin J, 2003. Adhesion of normal and Plasmodium falciparum ring-infected erythrocytes to endothelial cells and the placenta involves the rhoptry-derived ring surface protein-2. Blood 101: 5025–5032.
-
10.
Pouvelle B, Buffet PA, Lepolard C, Scherf A, Gysin J, 2000. Cytoadhesion of Plasmodium falciparum ring-stage-infected erythrocytes. Nat Med 6: 1264–1268.
-
11.
Scherf A, Pouvelle B, Buffet PA, Gysin J, 2001. Molecular mechanisms of Plasmodium falciparum placental adhesion. Cell Microbiol 3: 125–131.
-
12.
Bordbar B et al. 2014. Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria. Infect Genet Evol 25: 81–92.
-
13.
Salanti A, Staalsoe T, Lavstsen T, Jensen AT, Sowa MP, Arnot DE, Hviid L, Theander TG, 2003. Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Mol Microbiol 49: 179–191.
-
14.
Brabin BJ, 1983. An analysis of malaria in pregnancy in Africa. Bull World Health Organ 61: 1005–1016.
-
15.
Eisele TP, Larsen DA, Anglewicz PA, Keating J, Yukich J, Bennett A, Hutchinson P, Steketee RW, 2012. Malaria prevention in pregnancy, birthweight, and neonatal mortality: a meta-analysis of 32 national cross-sectional datasets in Africa. Lancet Infect Dis 12: 942–949.
-
16.
Rogerson SJ, Hviid L, Duffy PE, Leke RF, Taylor DW, 2007. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis 7: 105–117.
-
17.
Clausen TM et al. 2012. Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria. J Biol Chem 287: 23332–23345.
-
18.
Bordbar B, Tuikue-Ndam N, Bigey P, Doritchamou J, Scherman D, Deloron P, 2012. Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies. Vaccine 30: 1343–1348.
-
19.
EVI, 2017. European Vaccine Initiative - PRIMALVAC. Available at: http://www.euvaccine.eu/node/155/. Accessed June 15, 2017.
-
20.
EVI, 2017. European Vaccine Initiative - PlacMalVac. Available at: http://www.euvaccine.eu/node/156/. Accessed June 15, 2017.
-
21.
Patel JC et al. 2017. Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade. Sci Rep 7: 7768.
-
22.
Arango EM, Samuel R, Agudelo OM, Carmona-Fonseca J, Maestre A, Yanow SK, 2012. Genotype comparison of Plasmodium vivax and Plasmodium falciparum clones from pregnant and non-pregnant populations in North-west Colombia. Malar J 11: 392.
-
23.
Cohee LM, Kalilani-Phiri L, Mawindo P, Joshi S, Adams M, Kenefic L, Jacob CG, Taylor TE, Laufer MK, 2016. Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection. Malar J 15: 483.
-
24.
Guitard J, Andersen P, Ermont C, Gnidehou S, Fievet N, Lund O, Deloron P, Ndam NT, 2010. Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal. Malar J 9: 165.
-
25.
Jafari-Guemouri S, Ndam NT, Bertin G, Renart E, Sow S, Le Hesran JY, Deloron P, 2005. Demonstration of a high level of parasite population homology by quantification of Plasmodium falciparum alleles in matched peripheral, placental, and umbilical cord blood samples. J Clin Microbiol 43: 2980–2983.
-
26.
Kamwendo DD, Dzinjalamala FK, Snounou G, Kanjala MC, Mhango CG, Molyneux ME, Rogerson SJ, 2002. Plasmodium falciparum: PCR detection and genotyping of isolates from peripheral, placental, and cord blood of pregnant Malawian women and their infants. Trans R Soc Trop Med Hyg 96: 145–149.
-
27.
Kassberger F, Birkenmaier A, Khattab A, Kremsner PG, Klinkert MQ, 2002. PCR typing of Plasmodium falciparum in matched peripheral, placental and umbilical cord blood. Parasitol Res 88: 1073–1079.
-
28.
Mayengue PI, Rieth H, Khattab A, Issifou S, Kremsner PG, Klinkert MQ, Ntoumi F, 2004. Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women. Trop Med Int Health 9: 949–958.
-
29.
Schleiermacher D, Le Hesran JY, Ndiaye JL, Perraut R, Gaye A, Mercereau-Puijalon O, 2002. Hidden Plasmodium falciparum parasites in human infections: different genotype distribution in the peripheral circulation and in the placenta. Infect Genet Evol 2: 97–105.
-
30.
Serra-Casas E et al. 2011. Persistence of Plasmodium falciparum parasites in infected pregnant Mozambican women after delivery. Infect Immun 79: 298–304.
-
31.
Huynh BT, Fievet N, Gbaguidi G, Dechavanne S, Borgella S, Guezo-Mevo B, Massougbodji A, Ndam NT, Deloron P, Cot M, 2011. Influence of the timing of malaria infection during pregnancy on birth weight and on maternal anemia in Benin. Am J Trop Med Hyg 85: 214–220.
-
32.
Doritchamou J, Bertin G, Moussiliou A, Bigey P, Viwami F, Ezinmegnon S, Fievet N, Massougbodji A, Deloron P, Tuikue Ndam N, 2012. First-trimester Plasmodium falciparum infections display a typical “placental” phenotype. J Infect Dis 206: 1911–1919.
-
33.
Magistrado PA et al. 2011. High efficacy of anti DBL4varepsilon-VAR2CSA antibodies in inhibition of CSA-binding Plasmodiumfalciparum-infected erythrocytes from pregnant women. Vaccine 29: 437–443.
-
34.
Moore JM, Nahlen B, Ofulla AV, Caba J, Ayisi J, Oloo A, Misore A, Nahmias AJ, Lal AA, Udhayakumar V, 1997. A simple perfusion technique for isolation of maternal intervillous blood mononuclear cells from human placentae. J Immunol Methods 209: 93–104.
-
35.
Work TT, Jacobs JM, Spence JR, Volney WJ, 2010. High levels of green-tree retention are required to preserve ground beetle biodiversity in boreal mixedwood forests. Ecol Appl 20: 741–751.
-
36.
Oksanen J et al. 2016. Vegan: Community Ecology Package. R package version 2.4-1. Available at: https://cran.r-project.org/web/packages/vegan/index.html. Accessed November 15, 2016.
-
37.
Jombart T, Ahmed I, 2011. adegenet 1.3-1: new tools for the analysis of genome-wide SNP data. Bioinformatics 27: 3070–3071.
-
38.
Pfeifer B, Wittelsburger U, Ramos-Onsins SE, Lercher MJ, 2014. PopGenome: an efficient Swiss army knife for population genomic analyses in R. Mol Biol Evol 31: 1929–1936.
-
39.
Thompson JM, Irgens LM, Skjaerven R, Rasmussen S, 2007. Placenta weight percentile curves for singleton deliveries. BJOG 114: 715–720.
-
40.
Walker PG, Griffin JT, Cairns M, Rogerson SJ, van Eijk AM, ter Kuile F, Ghani AC, 2013. A model of parity-dependent immunity to placental malaria. Nat Commun 4: 1609.
-
41.
Beeson JG, Brown GV, Molyneux ME, Mhango C, Dzinjalamala F, Rogerson SJ, 1999. Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties. J Infect Dis 180: 464–472.
-
42.
Fried M, Duffy PE, 1996. Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 272: 1502–1504.
-
43.
Ofori MF, Staalsoe T, Bam V, Lundquist M, David KP, Browne EN, Akanmori BD, Hviid L, 2003. Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection. Infect Immun 71: 1584–1586.
-
44.
Doritchamou J, Sossou-tchatcha S, Cottrell G, Moussiliou A, Hounton Houngbeme C, Massougbodji A, Deloron P, Ndam NT, 2014. Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy. PLoS One 9: e98577.
-
45.
Kraemer SM et al. 2007. Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates. BMC Genomics 8: 45.
-
46.
Brolin KJ, Ribacke U, Nilsson S, Ankarklev J, Moll K, Wahlgren M, Chen Q, 2009. Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites. Genome Biol 10: R117.
-
47.
Sander AF, Salanti A, Lavstsen T, Nielsen MA, Magistrado P, Lusingu J, Ndam NT, Arnot DE, 2009. Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates. PLoS One 4: e6667.
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Matched Placental and Circulating Plasmodium falciparum Parasites are Genetically Homologous at the var2csa ID1-DBL2X Locus by Deep Sequencing
Andreea Waltmann
Andreea Waltmann
Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, North Carolina;
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Jaymin C. Patel
Jaymin C. Patel
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
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Kyaw L. Thwai
Kyaw L. Thwai
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
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Nicholas J. Hathaway
Nicholas J. Hathaway
Program in Bioinformatics and Integrative Biology, University of Massachusetts, Worcester, Massachusetts;
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Christian M. Parobek
Christian M. Parobek
Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina;
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Achille Massougbodji
Achille Massougbodji
Centre d'Etude et de Recherche sur le paludisme associé à la Grossesse et à l'Enfance, Université d'Abomey-Calavi, Cotonou, Benin;
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Nadine Fievet
Nadine Fievet
UMR216 - MERIT, Institut de Recherche pour le Développement, COMUE Sorbonne Paris Cité, Université Paris Descartes, Paris, France;
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Jeffery A. Bailey
Jeffery A. Bailey
Program in Bioinformatics and Integrative Biology, University of Massachusetts, Worcester, Massachusetts;
Division of Transfusion Medicine, Department of Medicine, University of Massachusetts, Worcester, Massachusetts
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Division of Transfusion Medicine, Department of Medicine, University of Massachusetts, Worcester, Massachusetts
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Philippe Deloron
Philippe Deloron
UMR216 - MERIT, Institut de Recherche pour le Développement, COMUE Sorbonne Paris Cité, Université Paris Descartes, Paris, France;
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Jonathan J. Juliano
Jonathan J. Juliano
Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, North Carolina;
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina;
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Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
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Nicaise Tuikue Ndam
Nicaise Tuikue Ndam
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Steven R. Meshnick
Steven R. Meshnick
Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, North Carolina;
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
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Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina;
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In pregnancy-associated malaria, infected erythrocytes accumulate in the placenta. It is unclear if in polyclonal infections this results in distinct peripheral and placental parasite populations. We used long amplicon deep sequencing of Plasmodium falciparum var2csa ID1-DBL2X from 15 matched peripheral and placental samples collected at delivery from a high transmission area to determine genetic homology. Despite substantial sequence variation and detecting 23 haplotypes, the matched pairs mostly contained the same genetic variants, with 11 pairs sharing 100% of their variants, whereas others showed some heterogeneity. Thus, at delivery, peripheral and placental parasites appear to intermix and placental genotypes can be inferred through peripheral sampling.
- Supplemental Materials (PDF 585 KB)
Author Notes
Financial support: This work was supported by National Institutes of Health and the National Institute of Allergy and Infectious Diseases under award number R56 AI106129 01A1 (to S. R. M.). This work relies on a previous work undertaken in the context of the STOPPAM project, “Strategies to Prevent Pregnancy Associated Malaria” supported by the European Union Framework 7 (STOPPAM) contract number: 200889. The information has not been previously presented at a scientific meeting.
Authors’ addresses: Andreea Waltmann, Department of Medicine, Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, NC, E-mail: waltmann@unc.edu. Jaymin C. Patel and Kyaw L. Thwai, Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, E-mails: jaymin86@gmail.com and thwai@email.unc.edu. Nicholas J. Hathaway, School of Medicine, University of Massachusetts Medical School, Worcester, MA, E-mail: nickjhathaway@gmail.com. Christian M. Parobek, Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, E-mail: christian.parobek@gmail.com. Achille Massougbodji, Faculté des Sciences de la Santé, Centre d’étude et de recherche sur le paludisme associé à la grossesse et à l’enfance (CERPAGE), Université d’Abomey-Calavi, Cotonou, Benin, E-mail: massougbodjiachille@yahoo.fr. Nadine Fievet, Institut de Recherche pour le Développement, UMR 216, Paris, France and Faculté des sciences de la Santé, Laboratoire de parasitology, Cotonou, Benin, E-mail: fievet@ird.fr. Jeffery A. Bailey, Department of Medicine, Division of Transfusion and Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, E-mail: jeffrey.bailey@umassmed.edu. Philippe Deloron, Institut de Recherche pour le Developpment, UR010, Faculté de Pharmacie, Paris, France, E-mail: philippe.deloron@ird.fr. Jonathan J. Juliano, Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, E-mail: jonathan_juliano@med.unc.edu. Nicaise Tuikue Ndam, Institut de Recherche pour le Développement, UMR 216, Paris, France and Faculté de Pharmacie, Université Paris descartes, Paris, France, E-mail: nicaise.ndam@ird.fr. Steven R. Meshnick, Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC and Department of Medicine, Institute for Global Health and Infectious Diseases, Chapel Hill, NC, E-mail: meshnick@live.unc.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Taylor SM et al. 2011. Quantification of the burden and consequences of pregnancy-associated malaria in the Democratic Republic of the Congo. J Infect Dis 204: 1762–1771.
-
2.
Miller LH, Baruch DI, Marsh K, Doumbo OK, 2002. The pathogenic basis of malaria. Nature 415: 673–679.
-
3.
Steketee RW, Nahlen BL, Parise ME, Menendez C, 2001. The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg 64: 28–35.
-
4.
van Geertruyden JP, Thomas F, Erhart A, D’Alessandro U, 2004. The contribution of malaria in pregnancy to perinatal mortality. Am J Trop Med Hyg 71: 35–40.
-
5.
Desai M, ter Kuile FO, Nosten F, McGready R, Asamoa K, Brabin B, Newman RD, 2007. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 7: 93–104.
-
6.
Ayres Pereira M et al. 2016. Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on Syndecan-1. PLoS Pathog 12: e1005831.
-
7.
Salanti A et al. 2004. Evidence for the involvement of VAR2CSA in pregnancy-associated malaria. J Exp Med 200: 1197–1203.
-
8.
Beeson JG, Amin N, Kanjala M, Rogerson SJ, 2002. Selective accumulation of mature asexual stages of Plasmodium falciparum-infected erythrocytes in the placenta. Infect Immun 70: 5412–5415.
-
9.
Douki JB, Sterkers Y, Lepolard C, Traore B, Costa FT, Scherf A, Gysin J, 2003. Adhesion of normal and Plasmodium falciparum ring-infected erythrocytes to endothelial cells and the placenta involves the rhoptry-derived ring surface protein-2. Blood 101: 5025–5032.
-
10.
Pouvelle B, Buffet PA, Lepolard C, Scherf A, Gysin J, 2000. Cytoadhesion of Plasmodium falciparum ring-stage-infected erythrocytes. Nat Med 6: 1264–1268.
-
11.
Scherf A, Pouvelle B, Buffet PA, Gysin J, 2001. Molecular mechanisms of Plasmodium falciparum placental adhesion. Cell Microbiol 3: 125–131.
-
12.
Bordbar B et al. 2014. Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria. Infect Genet Evol 25: 81–92.
-
13.
Salanti A, Staalsoe T, Lavstsen T, Jensen AT, Sowa MP, Arnot DE, Hviid L, Theander TG, 2003. Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Mol Microbiol 49: 179–191.
-
14.
Brabin BJ, 1983. An analysis of malaria in pregnancy in Africa. Bull World Health Organ 61: 1005–1016.
-
15.
Eisele TP, Larsen DA, Anglewicz PA, Keating J, Yukich J, Bennett A, Hutchinson P, Steketee RW, 2012. Malaria prevention in pregnancy, birthweight, and neonatal mortality: a meta-analysis of 32 national cross-sectional datasets in Africa. Lancet Infect Dis 12: 942–949.
-
16.
Rogerson SJ, Hviid L, Duffy PE, Leke RF, Taylor DW, 2007. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis 7: 105–117.
-
17.
Clausen TM et al. 2012. Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria. J Biol Chem 287: 23332–23345.
-
18.
Bordbar B, Tuikue-Ndam N, Bigey P, Doritchamou J, Scherman D, Deloron P, 2012. Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies. Vaccine 30: 1343–1348.
-
19.
EVI, 2017. European Vaccine Initiative - PRIMALVAC. Available at: http://www.euvaccine.eu/node/155/. Accessed June 15, 2017.
-
20.
EVI, 2017. European Vaccine Initiative - PlacMalVac. Available at: http://www.euvaccine.eu/node/156/. Accessed June 15, 2017.
-
21.
Patel JC et al. 2017. Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade. Sci Rep 7: 7768.
-
22.
Arango EM, Samuel R, Agudelo OM, Carmona-Fonseca J, Maestre A, Yanow SK, 2012. Genotype comparison of Plasmodium vivax and Plasmodium falciparum clones from pregnant and non-pregnant populations in North-west Colombia. Malar J 11: 392.
-
23.
Cohee LM, Kalilani-Phiri L, Mawindo P, Joshi S, Adams M, Kenefic L, Jacob CG, Taylor TE, Laufer MK, 2016. Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection. Malar J 15: 483.
-
24.
Guitard J, Andersen P, Ermont C, Gnidehou S, Fievet N, Lund O, Deloron P, Ndam NT, 2010. Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal. Malar J 9: 165.
-
25.
Jafari-Guemouri S, Ndam NT, Bertin G, Renart E, Sow S, Le Hesran JY, Deloron P, 2005. Demonstration of a high level of parasite population homology by quantification of Plasmodium falciparum alleles in matched peripheral, placental, and umbilical cord blood samples. J Clin Microbiol 43: 2980–2983.
-
26.
Kamwendo DD, Dzinjalamala FK, Snounou G, Kanjala MC, Mhango CG, Molyneux ME, Rogerson SJ, 2002. Plasmodium falciparum: PCR detection and genotyping of isolates from peripheral, placental, and cord blood of pregnant Malawian women and their infants. Trans R Soc Trop Med Hyg 96: 145–149.
-
27.
Kassberger F, Birkenmaier A, Khattab A, Kremsner PG, Klinkert MQ, 2002. PCR typing of Plasmodium falciparum in matched peripheral, placental and umbilical cord blood. Parasitol Res 88: 1073–1079.
-
28.
Mayengue PI, Rieth H, Khattab A, Issifou S, Kremsner PG, Klinkert MQ, Ntoumi F, 2004. Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women. Trop Med Int Health 9: 949–958.
-
29.
Schleiermacher D, Le Hesran JY, Ndiaye JL, Perraut R, Gaye A, Mercereau-Puijalon O, 2002. Hidden Plasmodium falciparum parasites in human infections: different genotype distribution in the peripheral circulation and in the placenta. Infect Genet Evol 2: 97–105.
-
30.
Serra-Casas E et al. 2011. Persistence of Plasmodium falciparum parasites in infected pregnant Mozambican women after delivery. Infect Immun 79: 298–304.
-
31.
Huynh BT, Fievet N, Gbaguidi G, Dechavanne S, Borgella S, Guezo-Mevo B, Massougbodji A, Ndam NT, Deloron P, Cot M, 2011. Influence of the timing of malaria infection during pregnancy on birth weight and on maternal anemia in Benin. Am J Trop Med Hyg 85: 214–220.
-
32.
Doritchamou J, Bertin G, Moussiliou A, Bigey P, Viwami F, Ezinmegnon S, Fievet N, Massougbodji A, Deloron P, Tuikue Ndam N, 2012. First-trimester Plasmodium falciparum infections display a typical “placental” phenotype. J Infect Dis 206: 1911–1919.
-
33.
Magistrado PA et al. 2011. High efficacy of anti DBL4varepsilon-VAR2CSA antibodies in inhibition of CSA-binding Plasmodiumfalciparum-infected erythrocytes from pregnant women. Vaccine 29: 437–443.
-
34.
Moore JM, Nahlen B, Ofulla AV, Caba J, Ayisi J, Oloo A, Misore A, Nahmias AJ, Lal AA, Udhayakumar V, 1997. A simple perfusion technique for isolation of maternal intervillous blood mononuclear cells from human placentae. J Immunol Methods 209: 93–104.
-
35.
Work TT, Jacobs JM, Spence JR, Volney WJ, 2010. High levels of green-tree retention are required to preserve ground beetle biodiversity in boreal mixedwood forests. Ecol Appl 20: 741–751.
-
36.
Oksanen J et al. 2016. Vegan: Community Ecology Package. R package version 2.4-1. Available at: https://cran.r-project.org/web/packages/vegan/index.html. Accessed November 15, 2016.
-
37.
Jombart T, Ahmed I, 2011. adegenet 1.3-1: new tools for the analysis of genome-wide SNP data. Bioinformatics 27: 3070–3071.
-
38.
Pfeifer B, Wittelsburger U, Ramos-Onsins SE, Lercher MJ, 2014. PopGenome: an efficient Swiss army knife for population genomic analyses in R. Mol Biol Evol 31: 1929–1936.
-
39.
Thompson JM, Irgens LM, Skjaerven R, Rasmussen S, 2007. Placenta weight percentile curves for singleton deliveries. BJOG 114: 715–720.
-
40.
Walker PG, Griffin JT, Cairns M, Rogerson SJ, van Eijk AM, ter Kuile F, Ghani AC, 2013. A model of parity-dependent immunity to placental malaria. Nat Commun 4: 1609.
-
41.
Beeson JG, Brown GV, Molyneux ME, Mhango C, Dzinjalamala F, Rogerson SJ, 1999. Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties. J Infect Dis 180: 464–472.
-
42.
Fried M, Duffy PE, 1996. Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 272: 1502–1504.
-
43.
Ofori MF, Staalsoe T, Bam V, Lundquist M, David KP, Browne EN, Akanmori BD, Hviid L, 2003. Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection. Infect Immun 71: 1584–1586.
-
44.
Doritchamou J, Sossou-tchatcha S, Cottrell G, Moussiliou A, Hounton Houngbeme C, Massougbodji A, Deloron P, Ndam NT, 2014. Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy. PLoS One 9: e98577.
-
45.
Kraemer SM et al. 2007. Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates. BMC Genomics 8: 45.
-
46.
Brolin KJ, Ribacke U, Nilsson S, Ankarklev J, Moll K, Wahlgren M, Chen Q, 2009. Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites. Genome Biol 10: R117.
-
47.
Sander AF, Salanti A, Lavstsen T, Nielsen MA, Magistrado P, Lusingu J, Ndam NT, Arnot DE, 2009. Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates. PLoS One 4: e6667.
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