ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Hetzel MW, Choudhury AA, Pulford J, Ura Y, Whittaker M, Siba PM, Mueller I, 2014. Progress in mosquito net coverage in Papua New Guinea. Malar J 13: 242.
-
2.
Hetzel MW et al. 2017. Insecticide-treated nets and malaria prevalence, Papua New Guinea, 2008–2014. Bull World Health Organ 95: 695–705B.
-
3.
Hetzel MW, Reimer LJ, Gideon G, Koimbu G, Barnadas C, Makita L, Siba PM, Mueller I, 2016. Changes in malaria burden and transmission in sentinel sites after the roll-out of long-lasting insecticidal nets in Papua New Guinea. Parasit Vectors 9: 340.
-
4.
Ranson H, Lissenden N, 2016. Insecticide resistance in African Anopheles mosquitoes: a worsening situation that needs urgent action to maintain malaria control. Trends Parasitol 32: 187–196.
-
5.
Chaumeau V, Cerqueira D, Zadrozny J, Kittiphanakun P, Andolina C, Chareonviriyaphap T, Nosten F, Corbel V, 2017. Insecticide resistance in malaria vectors along the Thailand-Myanmar border. Parasit Vectors 10: 165.
-
6.
Hemingway J, Hawkes NJ, McCarroll L, Ranson H, 2004. The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Mol Biol 34: 653–665.
-
7.
Keven JB, Henry-Halldin CN, Thomsen EK, Mueller I, Siba PM, Zimmerman PA, Reimer LJ, 2010. Pyrethroid susceptibility in natural populations of the Anopheles punctulatus group (Diptera: Culicidae) in Papua New Guinea. Am J Trop Med Hyg 83: 1259–1261.
-
8.
Reimer LJ, Thomsen EK, Koimbu G, Keven JB, Mueller I, Siba PM, Kazura JW, Hetzel MW, Zimmerman PA, 2016. Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea. Malar J 15: 25.
-
9.
Thomsen EK, Koimbu G, Pulford J, Jamea-Maiasa S, Ura Y, Keven JB, Siba PM, Mueller I, Hetzel MW, Reimer LJ, 2016. Mosquito behaviour change after distribution of bednets results in decreased protection against malaria exposure. J Infect Dis 215: 790–797.
-
10.
Parkinson AD, 1974. Malaria in Papua New Guinea 1973. P N G Med J 17: 8–16.
-
11.
Nardini L, Christian RN, Coetzer N, Koekemoer LL, 2013. DDT and pyrethroid resistance in Anopheles arabiensis from South Africa. Parasit Vectors 6: 229.
-
12.
WHO, 2013. Test Procedures for Insecticide Resistance Monitoring in Malaria Vector Mosquitoes. Geneva, Switzerland: World Health Organization.
-
13.
Lukwa N, Sande S, Munosiyei P, Zimba M, 2012. Insecticide susceptibility tests conducted in Kamhororo, Masakadza and Chilonga villages in Zimbabwe during the 2011 malaria period. J Entomol Acarol Res 44: e19.
-
14.
Hetzel MW et al. 2014. Evaluation of the Global Fund-supported National Malaria Control Program in Papua New Guinea, 2009-2014. P N G Med J 57: 7–29.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1 | 1 | 1 |
| Full Text Views | 878 | 483 | 3 |
| PDF Downloads | 90 | 29 | 3 |
Status of Insecticide Resistance in Papua New Guinea: An Update from Nation-Wide Monitoring of Anopheles Mosquitoes
Insecticide resistance (IR) monitoring is an important component of vector-borne disease control. The last assessment of IR in Papua New Guinea (PNG) was conducted in 2010. Since then, vector populations have been exposed to higher levels of pyrethroids with the continued nation-wide distribution of insecticide-treated nets. Here, we provide an update on phenotypic IR in four highly malaria-endemic areas of PNG. IR against deltamethrin, lambda-cyhalothrin, and dichlorodiphenyltrichloroethane was assessed using World Health Organization bioassays. A total of 108 bioassays for each insecticide were conducted screening 2,290 adult female anopheline mosquitoes. No phenotypic resistance was observed. Bioassay parameters agreed well with those observed in other studies that used the same assays and insecticides. These results indicate that the three tested insecticides are still universally effective in PNG. Continued IR monitoring (every 1–2 years) in PNG is recommended to detect reduced susceptibility early and adjust guidelines to prevent widespread resistance.
- Supplemental Materials (PDF 20 KB)
Author Notes
Financial support: The present study was conducted with the financial support of the Global Fund to Fight AIDS, Tuberculosis and Malaria and logistical and administrative support from Population Services International (PSI). The authors acknowledge the support of the MSCU, in particular that of Melinda Susapu.
Authors’ addresses: Gussy Koimbu, Cyrille Czeher, Michelle Katusele, Muker Sakur, Lemen Kilepak, and Anthony Tandrapah, Vector-borne Infectious Diseases Unit, Papua New Guinea Institute of Medical Research, Madang, Madang 511, Papua New Guinea, E-mails: gkoimbu@hotmail.com, cyril_czeher@yahoo.fr, katuselemn@gmail.com, muker.sakur@gmail.com, lemen.kilepak@gmail.com, and anthony.tandrapah@pngimr.org.pg. Manuel W. Hetzel, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland, E-mail: manuel.hetzel@swisstph.ch. Justin Pulford, Liverpool School of Tropical Medicine, Pembroke Place Liverpool, L3 5QA United Kingdom, E-mail: justin.pulford@lstmed.ac.uk. Leanne Robinson, Disease Elimination Program, Burnet Institute, 85 Commercial Road, Melbourne Victoria, 3004, Australia, Department of Population Health & Immunity, 1G Royal Parade, Parkville Victoria 3052, Australia, and Department of Medical Biology, University of Melbourne, Grattan Street, Parkville, Victoria, 3010, Australia, E-mail: leanne.robinson@burnet.edu.au. Stephan Karl, Department of Population Health & Immunity, Walter & Eliza Hall Institute, 1G Royal Parade, Parkville Victoria 3052, Australia, Vector-borne Infectious Diseases Unit, Papua New Guinea Institute of Medical Research, Madang, Madang 511, Papua New Guinea, and Department of Medical Biology, University of Melbourne, Grattan Street, Parkville, Victoria, 3010, Australia, E-mail: karl@wehi.edu.au.
These authors contributed equally to this work.