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Rocky Mountain Spotted Fever and Pregnancy: Four Cases from Sonora, Mexico

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  • 1 Department of Medicine and Health Sciences, University of Sonora, Hermosillo, Mexico;
  • | 2 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia;
  • | 3 Women’s Health Hospital of Sonora State, Hermosillo, Mexico

We present a series of four pregnant women with Rocky Mountain spotted fever (RMSF) that occurred in Sonora, Mexico, during 2015–2016. Confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of Rickettsia rickettsii by using an indirect immunofluorescence antibody assay. Each patient presented with fever and petechial rash and was treated successfully with doxycycline. Each of the women and one full-term infant delivered at 36 weeks gestation survived the infection. Three of the patients in their first trimester of pregnancy suffered spontaneous abortions. RMSF should be suspected in any pregnant woman presenting with fever, malaise and rash in regions where R. rickettsii is endemic.

Author Notes

Address correspondence to Gerardo Álvarez Hernández, Boulevard Luis D. Colosio SN, col. Centro, C.P. 83000, Hermosillo, Sonora, Mexico. E-mail: galvarezh63@gmail.com

Authors’ addresses: Jesus D. Licona-Enriquez, Jesus Delgado-de la Mora, Maria del Carmen Candia-Plata, and Gerardo Álvarez Hernández, Departamento de Medicina y Ciencias de la Salud, Universidad de Sonora, Hermosillo, Mexico, E-mails: jdliconae@gmail.com, jdelgadom@live.com.mx, carmenc@guayacan.uson.mx, and galvarezh63@gmail.com. Christopher D. Paddock, Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA, E-mail: cdp9@cdc.gov. Carlos Arturo Ramirez-Rodriguez, Women’s Health Hospital of Sonora State, Hermosillo, Mexico, E-mail: drcarlos1958@hotmail.com.

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